Salicylidene salicylhydrazide (SCS) - Moligand™, ≥97% , CAS No.3232-36-8

CAS: 3232-36-8 Cat. No.: S287391 Molecular Weight: 256.26 EC Number: 221-773-2 PubChem CID: 135445765
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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
Synonyms
N-Salicylidene-N'-salicyloylhydrazine | N-Salicylidene-N-salicyloylhydrazine | SR-01000872611-3 | SALICYLIDENESALICYLHYDRAZIDE | 2-Hydroxy-N'-[(E)-(2-hydroxyphenyl)methylidene]benzohydrazide | 2-HYDROXY-N'~1~-[(2-HYDROXYPHENYL)METHYLENE]BENZOHYDRAZIDE | S
Storage
Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1g
S287391-1g
3

$22.90

$26.90
Save $4.00 (14.87%)
5g
S287391-5g
2
$89.90
25g
S287391-25g
1
$359.90
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, ≥97% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
N-Salicylidene-N'-salicyloylhydrazine | N-Salicylidene-N-salicyloylhydrazine | SR-01000872611-3 | SALICYLIDENESALICYLHYDRAZIDE | 2-Hydroxy-N'-[(E)-(2-hydroxyphenyl)methylidene]benzohydrazide | 2-HYDROXY-N'~1~-[(2-HYDROXYPHENYL)METHYLENE]BENZOHYDRAZIDE | S
Specifications & Purity
Moligand™, ≥97%
Biochemical and Physiological Mechanisms
Potent and selective partial inhibitor ofβ1-containing GABAAreceptors (IC50values are 4.5, 5.3 and 7.9 nM atα2β1γ1θ, α2β1γ1 andα2β1γ2s GABAAreceptors respectively). May bind allosterically to a novel site on GABAAreceptor.
Storage
Room temperature
Shipped In
Normal
Grade
Moligand™
Purity
≥97%
Names and Identifiers
Pubchem Sid504773333
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504773333
Canonical SmilesC1=CC=C(C(=C1)C=NNC(=O)C2=CC=CC=C2O)O
IUPAC Name2-hydroxy-N-[(E)-(2-hydroxyphenyl)methylideneamino]benzamide
InChIKeyOMCYEZUIYGPHDJ-OQLLNIDSSA-N
INCHI1S/C14H12N2O3/c17-12-7-3-1-5-10(12)9-15-16-14(19)11-6-2-4-8-13(11)18/h1-9,17-18H,(H,16,19)/b15-9+
Isomeric SMILES C1=CC=C(C(=C1)/C=N/NC(=O)C2=CC=CC=C2O)O
PubChem CID 135445765
Molecular Weight 256.26

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassBenzene and substituted derivatives
SubclassBenzoic acids and derivatives
Intermediate Tree Nodes Hydroxybenzoic acid derivatives - Salicylic acid and derivatives
Direct ParentSalicylamides
Alternative Parents Benzoyl derivatives  1-hydroxy-4-unsubstituted benzenoids  1-hydroxy-2-unsubstituted benzenoids  Vinylogous acids  Carboxylic acids and derivatives  Organooxygen compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Salicylamide - Benzoyl - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Vinylogous acid - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as salicylamides. These are carboxamide derivatives of salicylic acid. Salicylic acid is the ortho-hydroxylated derivative of benzoic acid.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
pol Human immunodeficiency virus type 1 integrase (9041 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bacillus subtilis (32866 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycobacterium tuberculosis (203094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nakaseomyces glabratus (9108 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
J774 (3120 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Luciferin 4-monooxygenase (66902 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeDateItem
F2417483Certificate of AnalysisFeb 29, 2024 S287391
F2417484Certificate of AnalysisFeb 29, 2024 S287391
F2417485Certificate of AnalysisFeb 29, 2024 S287391
F2417486Certificate of AnalysisFeb 29, 2024 S287391
F2417487Certificate of AnalysisFeb 29, 2024 S287391
F2417488Certificate of AnalysisFeb 29, 2024 S287391
Chemical and Physical Properties
SolubilitySolvent:DMSO, Max Conc. mg/mL: 12.81, Max Conc. mM: 50
Molecular Weight256.260 g/mol
XLogP32.700
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass256.085 Da
Monoisotopic Mass256.085 Da
Topological Polar Surface Area81.900 Ų
Heavy Atom Count19
Formal Charge0
Complexity333.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds1
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Cheng Li, Yang Tian, Jiahuan Pei, Yuyang Zhang, Daokuan Hao, Tianjiao Han, Xiaoqin Wang, Shuang Song, Linjuan Huang, Zhongfu Wang.  (2023)  Sea cucumber chondroitin sulfate polysaccharides attenuate OVA-induced food allergy in BALB/c mice associated with gut microbiota metabolism and Treg cell differentiation.  Food & Function,  14  (16): (7375-7386).  [PMID:37477050] [10.1039/D3FO00146F]
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