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· · COA & SDS available for every product · Same-day shipping on in-stock items SCH 51344 - ≥99%(HPLC) , CAS No.171927-40-5
Synonyms
BCP17385 | EX-A4182 | WGA92740 | Ras/Rac Transformation Blocker, SCH 51344 | HMS3674M09 | NCGC00384193-04 | 2-[2-[(6-Methoxy-3-methyl-1H-pyrazolo[3,4-b]quinolin-4-yl)amino]ethoxy]ethanol | DTXSID10433926 | 2-(2-((6-methoxy-3-methyl-1H-pyrazolo[3,4-b]quino
Shipped In
Ice chest + Ice pads
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Why this grade ≥99%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
BCP17385 | EX-A4182 | WGA92740 | Ras/Rac Transformation Blocker, SCH 51344 | HMS3674M09 | NCGC00384193-04 | 2-[2-[(6-Methoxy-3-methyl-1H-pyrazolo[3, 4-b]quinolin-4-yl)amino]ethoxy]ethanol | DTXSID10433926 | 2-(2-((6-methoxy-3-methyl-1H-pyrazolo[3, 4-b]quino
Specifications & Purity
≥99%(HPLC)
Biochemical and Physiological Mechanisms
Potent MTH1 inhibitor (Kd= 49 nM). Inhibits Ras-induced malignant transformation and increasesα-actin promoter-driven CAT activity in Ras-transformed cells. Has no effect on Ras-induced ERK and JNK activation. Inhibits Ras-induced membrane ruffling in REF
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers Canonical Smiles CC1=C2C(=C3C=C(C=CC3=NC2=NN1)OC)NCCOCCO IUPAC Name 2-[2-[(6-methoxy-3-methyl-2H-pyrazolo[3,4-b]quinolin-4-yl)amino]ethoxy]ethanol InChIKey YWEGXZZAORIRQR-UHFFFAOYSA-N INCHI 1S/C16H20N4O3/c1-10-14-15(17-5-7-23-8-6-21)12-9-11(22-2)3-4-13(12)18-16(14)20-19-10/h3-4,9,21H,5-8H2,1-2H3,(H2,17,18,19,20) Isomeric SMILES CC1=C2C(=C3C=C(C=CC3=NC2=NN1)OC)NCCOCCO PubChem CID 9995890 Molecular Weight 316.35
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Quinolines and derivatives Subclass Aminoquinolines and derivatives Intermediate Tree Nodes Not available Direct Parent 4-aminoquinolines Alternative Parents Pyrazolopyridines Anisoles Secondary alkylarylamines Aminopyridines and derivatives Alkyl aryl ethers Pyrazoles Heteroaromatic compounds Dialkyl ethers Azacyclic compounds Primary alcohols Organopnictogen compounds Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents 4-aminoquinoline - Pyrazolopyridine - Anisole - Alkyl aryl ether - Aminopyridine - Secondary aliphatic/aromatic amine - Pyridine - Benzenoid - Azole - Pyrazole - Heteroaromatic compound - Ether - Dialkyl ether - Azacycle - Secondary amine - Hydrocarbon derivative - Organic nitrogen compound - Primary alcohol - Organooxygen compound - Organonitrogen compound - Alcohol - Organopnictogen compound - Organic oxygen compound - Amine - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as 4-aminoquinolines. These are organic compounds containing an amino group attached to the 4-position of a quinoline ring system. External Descriptors aromatic ether - secondary amino compound - primary alcohol - aromatic amine - pyrazoloquinoline Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 31.64, Max Conc. mM: 100 Molecular Weight 316.350 g/mol XLogP3 1.700 Hydrogen Bond Donor Count 3 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 7 Exact Mass 316.154 Da Monoisotopic Mass 316.154 Da Topological Polar Surface Area 92.300 Ų Heavy Atom Count 23 Formal Charge 0 Complexity 373.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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