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AR,Moligand™ AR,Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 23 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Serotonin hydrochloride is the salt form of Serotonin, a monoamine neurotransmitter biochemically derived from tryptophan. This neurotransmitter is located in the central nervous system and functions as an endogenous SR (serotonin receptor) agonist in a variety of biochemical processes. In the majority of the human bodies, serotonin is located in enterochromaffin (”Kulchitsky cells”). Serotonin is found in the gastrointestinal tract and platelets. Furthermore, Serotonin functions as a growth factor in some cells and facilitates wound healing in conjunction with platelets. Serotonin is thought to be a key component in the regulation of moods, cognition, and personality traits. As a result, this compound is essential in studying the variations in these traits.
A tryptophan based amino acid neurotransmitter.
| Canonical Smiles | C1=CC2=C(C=C1O)C(=CN2)CCN.Cl |
|---|---|
| IUPAC Name | 3-(2-aminoethyl)-1H-indol-5-ol;hydrochloride |
| InChIKey | MDIGAZPGKJFIAH-UHFFFAOYSA-N |
| INCHI | 1S/C10H12N2O.ClH/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10;/h1-2,5-6,12-13H,3-4,11H2;1H |
| Isomeric SMILES | C1=CC2=C(C=C1O)C(=CN2)CCN.Cl |
| WGK Germany | 3 |
| RTECS | NM2571000 |
| PubChem CID | 160436 |
| UN Number | 2811 |
| Molecular Weight | 212.68 |
| Beilstein | 3570963 |
| Reaxy-Rn | 3570963 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Indoles and derivatives |
| Subclass | Tryptamines and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Serotonins |
| Alternative Parents | Hydroxyindoles 3-alkylindoles 2-arylethylamines Aralkylamines 1-hydroxy-2-unsubstituted benzenoids Substituted pyrroles Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organooxygen compounds Monoalkylamines Hydrochlorides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Serotonin - Hydroxyindole - 3-alkylindole - Indole - 2-arylethylamine - 1-hydroxy-2-unsubstituted benzenoid - Aralkylamine - Substituted pyrrole - Benzenoid - Pyrrole - Heteroaromatic compound - Azacycle - Amine - Hydrochloride - Hydrocarbon derivative - Organopnictogen compound - Organic oxygen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Organic nitrogen compound - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as serotonins. These are compounds containing a serotonin moiety, which consists of an indole that bears an aminoethyl a position 2 and a hydroxyl group at position 5. |
| External Descriptors | Not available |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Apr 09, 2026 | S111161 | |
| Certificate of Analysis | Apr 09, 2026 | S111161 | |
| Certificate of Analysis | Apr 09, 2026 | S111161 | |
| Certificate of Analysis | Oct 07, 2023 | S111161 | |
| Certificate of Analysis | Oct 07, 2023 | S111161 | |
| Certificate of Analysis | Oct 07, 2023 | S111161 | |
| Certificate of Analysis | Oct 07, 2023 | S111161 | |
| Certificate of Analysis | Oct 07, 2023 | S111161 | |
| Certificate of Analysis | Oct 07, 2023 | S111161 | |
| Certificate of Analysis | Oct 07, 2023 | S111161 | |
| Certificate of Analysis | Jun 13, 2022 | S111161 | |
| Certificate of Analysis | Jun 13, 2022 | S111161 | |
| Certificate of Analysis | Jun 13, 2022 | S111161 |
| Solubility | Soluble in water (17 mg/ml), methanol, ethanol (5.3 mg/ml), 0.1 M HCl (22 mg/ml), aqueous acid, and DMSO (100 mM). Insoluble in chloroform, and ether. |
|---|---|
| Sensitivity | Moisture & Light sensitive |
| Melt Point(°C) | 168-172°C |
| Molecular Weight | 212.670 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 2 |
| Exact Mass | 212.072 Da |
| Monoisotopic Mass | 212.072 Da |
| Topological Polar Surface Area | 62.000 Ų |
| Heavy Atom Count | 14 |
| Formal Charge | 0 |
| Complexity | 174.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |
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| 5. Yong-Yi Zhao, Heng Li, Qing-Mei Ge, Hang Cong, Mao Liu, Zhu Tao, Jiang-Lin Zhao. (2020) A chemo-sensor constructed by nanohybrid of multifarene[3,3] and rGO for serotonin hydrochloride with dual response in both fluorescence and voltammetry. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2020.105145] |
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