Sulbactam - Moligand™, 10mM in DMSO , CAS No.68373-14-8

CAS: 68373-14-8 Cat. No.: S409091 Molecular Weight: 233.24 EC Number: 269-878-2

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

(2S,​5R)​-3,​3-​dimethyl-​7-​oxo-​4,​4-​dioxide-4-​thia-​1-​azabicyclo[3.2.0]​heptane-​2-​carboxylic acid

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Information

Sulbactam Sulbactam is a beta-lactamase inhibitor with an average IC50 of 0.8 μM.
In vitro

In vivo

Cell Data

cell lines：BaF3 cells

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Synonyms

(2S, ​5R)​-3, ​3-​dimethyl-​7-​oxo-​4, ​4-​dioxide-4-​thia-​1-​azabicyclo[3.2.0]​heptane-​2-​carboxylic acid

Specifications & Purity

Moligand™, 10mM in DMSO

Biochemical and Physiological Mechanisms

Sulbactam is a beta-lactamase inhibitor with an average IC50 of 0.8 μM.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Names and Identifiers

• Isomeric SMILES: CC1([C@@H](N2[C@H](S1(=O)=O)CC2=O)C(=O)O)C
• WGK Germany: 3
• Molecular Weight: 233.24
• Reaxy-Rn: 1128064
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1128064&ln=

Chemical and Physical Properties

• Solubility: Solubility (25°C) In vitro DMSO: 13 mg/mL warmed with 50ºC Water: bath (18.42 mM); Water: Insoluble; Ethanol: Insoluble
• Specific Rotation[α]: 237° (C=1,H2O)
• Melt Point(°C): 156 °C(dec.)

References

1. Li Xiaobo, Song Yanqing, Wang Lina, Kang Guangbo, Wang Ping, Yin Huabing, Huang He.  (2021)  A Potential Combination Therapy of Berberine Hydrochloride With Antibiotics Against Multidrug-Resistant Acinetobacter baumannii.  Frontiers in Cellular and Infection Microbiology,      [PMID:33842399] [10.3389/fcimb.2021.660431]

2. Qinyu Luo, Zehua Wu, Yihang Pan, Yan Zhang.  (2025)  Disulfiram inhibits bacterial growth by inducing zinc-dependent reactive oxygen species.  Frontiers in Microbiology,      [PMID:40746315] [10.3389/fmicb.2025.1619416]