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analytical standard Analytical standard for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 27 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| ALogP | 0.3 |
|---|
| Canonical Smiles | COC1=NN=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)N |
|---|---|
| IUPAC Name | 4-amino-N-(6-methoxypyridazin-3-yl)benzenesulfonamide |
| InChIKey | VLYWMPOKSSWJAL-UHFFFAOYSA-N |
| INCHI | 1S/C11H12N4O3S/c1-18-11-7-6-10(13-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,15) |
| Isomeric SMILES | COC1=NN=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)N |
| WGK Germany | 2 |
| RTECS | WP0400000 |
| PubChem CID | 5330 |
| Molecular Weight | 280.3 |
| Beilstein | 277076 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Benzenesulfonamides |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Aminobenzenesulfonamides |
| Alternative Parents | Benzenesulfonyl compounds Aniline and substituted anilines Alkyl aryl ethers Pyridazines and derivatives Organosulfonamides Imidolactams Heteroaromatic compounds Aminosulfonyl compounds Azacyclic compounds Primary amines Organopnictogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Aminobenzenesulfonamide - Benzenesulfonyl group - Aniline or substituted anilines - Alkyl aryl ether - Pyridazine - Organosulfonic acid amide - Imidolactam - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Sulfonyl - Aminosulfonyl compound - Heteroaromatic compound - Organoheterocyclic compound - Ether - Azacycle - Organic oxygen compound - Organic oxide - Amine - Organic nitrogen compound - Organopnictogen compound - Primary amine - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Aromatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as aminobenzenesulfonamides. These are organic compounds containing a benzenesulfonamide moiety with an amine group attached to the benzene ring. |
| External Descriptors | sulfonamide - pyridazines - sulfonamide antibiotic |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Sep 16, 2025 | S114298 | |
| Certificate of Analysis | Aug 11, 2025 | S114298 | |
| Certificate of Analysis | Aug 11, 2025 | S114298 | |
| Certificate of Analysis | Jul 15, 2024 | S114298 | |
| Certificate of Analysis | Jul 15, 2024 | S114298 | |
| Certificate of Analysis | Jul 15, 2024 | S114298 | |
| Certificate of Analysis | Jul 13, 2023 | S114298 |
| Melt Point(°C) | 180-183°C |
|---|---|
| Molecular Weight | 280.310 g/mol |
| XLogP3 | 0.300 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 4 |
| Exact Mass | 280.063 Da |
| Monoisotopic Mass | 280.063 Da |
| Topological Polar Surface Area | 116.000 Ų |
| Heavy Atom Count | 19 |
| Formal Charge | 0 |
| Complexity | 376.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Jiana Lin, Zenghui Xie, Yuling Hu, Gongke Li, Qisheng Zhong. (2023) Flower-like calix[6]arene-based covalent organic framework for membrane extraction of sulfonamides in animal-derived food through host-guest interaction prior to determination with ultra-high performance liquid chromatography-tandem mass spectrometry. JOURNAL OF CHROMATOGRAPHY A, [PMID:37983987] [10.1016/j.chroma.2023.464499] |
| 2. Jing Wang, Yong Zhang, Fubin Liu, Ying Liu, Litao Wang, Guihua Gao. (2023) Preparation of a Multifunctional and Multipurpose Chitosan/Cyclodextrin/MIL-68(Al) Foam Column and Examining Its Adsorption Properties for Anionic and Cationic Dyes and Sulfonamides. ACS Omega, [PMID:37692232] [10.1021/acsomega.3c03897] |
| 3. Meiling Ping, Wenchao Lv, Chen Yang, Qian Chen, Zongwen Wang, Fengfu Fu. (2023) A Paper-Based Multicolor Colorimetric Aptasensor for the Visual Determination of Multiple Sulfonamides Based on Aptamer-Functionalized Magnetic Beads and NADH–Ascorbic Acid-Mediated Gold Nanobipyramids. Chemosensors, 11 (7): (386). [PMID:] [10.3390/chemosensors11070386] |
| 4. Zongwen Wang, Xiating Li, Feng Zhang, Yu Gao, Jintian Cheng, FengFu Fu. (2023) Regulating the Growth Rate of Gold Nanobipyramids via a HCl-NADH-Ascorbic Acid System toward a Dual-Channel Multicolor Colorimetric Immunoassay for Simultaneously Screening and Detecting Multiple Sulfonamides. ANALYTICAL CHEMISTRY, [PMID:37382204] [10.1021/acs.analchem.3c01928] |
| 5. Dai Yongheng, Yuan Huayu, Li Jiang, Su Qi, Yi Qianwen, Zhang Yuntao. (2023) Direct Z-scheme P–TiO2/g-C3N4 heterojunction for the photocatalytic degradation of sulfa antibiotics. RSC Advances, 13 (9): (5957-5969). [PMID:36816086] [10.1039/D2RA07289K] |
| 6. Tang Jiaming, Zheng Xiaoling, Jiang Shuang, Cao Mingdong, Wang Sixian, Zhou Zhaoyang, Nie Xunqing, Fang Yu, Le Tao. (2022) Dual fluorescent aptasensor for simultanous and quantitative detection of sulfadimethoxine and oxytetracycin residues in animal-derived foods tissues based on mesoporous silica. Frontiers in Nutrition, [PMID:36618689] [10.3389/fnut.2022.1077893] |
| 7. Ligui Wu, Mingyu Wang, Lingling Rong, Wenbiao Wang, Linwei Chen, Qiaofeng Wu, Haoyu Sun, Xiangfeng Huang, Xiaoming Zou. (2022) Structural effects of sulfonamides on the proliferation dynamics of sulfonamide resistance genes in the sequencing batch reactors and the mechanism. Journal of Environmental Sciences, [PMID:37778792] [10.1016/j.jes.2022.11.014] |
| 8. Li Gang, Wu Ming-Huo, Liu Yan, Hu Yu-Feng. (2022) Facile fluorescent probe for simultaneous fluorescence detection of fluoroquinolones and copper. CHEMICAL PAPERS, 77 (3): (1423-1432). [PMID:] [10.1007/s11696-022-02568-4] |
| 9. Yawen Wang, Jingwen Huang, He Guo, Chendong Puyang, Jiangang Han, Yan Li, Yunxia Ruan. (2022) Mechanism and process of sulfamethoxazole decomposition with persulfate activated by pulse dielectric barrier discharge plasma. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2022.120540] |
| 10. Yang Wang, Xueyan Liu, Lei Zhang. (2019) Assembling 3D hierarchical hollow flower-like Ni@N-doped graphitic carbon for boosting simultaneously efficient removal and sensitive monitoring of multiple sulfonamides. JOURNAL OF HAZARDOUS MATERIALS, [PMID:31759760] [10.1016/j.jhazmat.2019.121629] |
| 11. Minghuo Wu, Lin Fu, Yufeng Hu, Jingyun Su, Siyuan Jing, Hao Zhou, Jingjing Zhan. (2018) Multiplex On-Bead Isotope Dimethyl Labeling Coupled with Liquid Chromatography–High-Resolution Mass Spectrometry for Quantitative Analysis of Sulfonamides in Estuarine Ice. ANALYTICAL CHEMISTRY, [PMID:30221932] [10.1021/acs.analchem.8b03220] |
| 12. Suyu Ren, Jing Tao, Feng Tan, Ying Cui, Xiaona Li, Jingwen Chen, Xin He, Yi Wang. (2018) Diffusive gradients in thin films based on MOF-derived porous carbon binding gel for in-situ measurement of antibiotics in waters. SCIENCE OF THE TOTAL ENVIRONMENT, [PMID:30029123] [10.1016/j.scitotenv.2018.07.013] |
| 13. Xiangfeng Huang, Yi Feng, Cui Hu, Xiaoyu Xiao, Daliang Yu, Xiaoming Zou. (2015) Mechanistic model for interpreting the toxic effects of sulfonamides on nitrification. JOURNAL OF HAZARDOUS MATERIALS, [PMID:26651069] [10.1016/j.jhazmat.2015.11.037] |
| 14. Lili Wang, Jing Wu, Qin Wang, Chonghui He, Lei Zhou, Jing Wang, Qiaosheng Pu. (2012) Rapid and Sensitive Determination of Sulfonamide Residues in Milk and Chicken Muscle by Microfluidic Chip Electrophoresis. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:22277081] [10.1021/jf2036577] |
| 15. Jingjing Yan, Wen Xie, Yingxue Jin, Zongwei Cai, Zian Lin. (2025) 1,4-Dioxo-1,2,3,4-tetrahydrophthalazine-6-carboxylic acid as a novel MALDI matrix for enhanced analysis of metabolites induced by imidacloprid exposure. TALANTA, [PMID:39765079] [10.1016/j.talanta.2025.127536] |
| 16. Renjie Pan, Zongchen Li, Tian-Yang Zhang, Qi Fu, Zheng-Xiong Zheng, Jun Shi, Jian Lu, Chen-Yan Hu, Yu-Lin Tang, Mohamed Gamal El-Din, Bin Xu. (2025) Amino-functionalized MIL-101(Fe)-NH2 as efficient peracetic acid activator for selective contaminant degradation: Unraveling the role of electron-donating ligands in Fe(IV) generation. JOURNAL OF HAZARDOUS MATERIALS, [PMID:40153961] [10.1016/j.jhazmat.2025.138028] |
| 17. Yue Zhou, Yuanyuan Jiang, Xiangyu Chen, Hongchen Long, Mao Zhang, Zili Tang, Yufang He, Lei Zhang, Tao Le. (2024) Enhanced Sensitivity and Accuracy of Tb3+-Functionalized Zirconium-Based Bimetallic MOF for Visual Detection of Malachite Green in Fish. Foods, 13 (17): (2855). [PMID:39272620] [10.3390/foods13172855] |
| 18. Linan Xu, Yifu Peng, Bin Zheng, Zhanqiang Fang. (2024) Nitrogen-sulfur co-doped magnetic biochar efficiently activates hydrogen peroxide for the degradation of sulfamethazine. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2024.155477] |
| 19. Yong Zhang, Jing Wang, Fubin Liu, Litao Wang, Guihua Gao. (2024) Preparation of cylindrical Chitosan/β-Cyclodextrin/MIL-68(Al) foam column for solid-phase extraction of sulfonamides in water, urine, and milk. JOURNAL OF CHROMATOGRAPHY A, [PMID:38955130] [10.1016/j.chroma.2024.465130] |
| 20. Chun-Ying Xu, Chang-Qing Zhen, Yu-Jing He, Yuan-Yuan Cui, Cheng-Xiong Yang. (2024) Solvent and monomer regulation synthesis of core-shelled magnetic β-cyclodextrin microporous organic network for efficient extraction of estrogens in biological samples prior to HPLC analysis. JOURNAL OF CHROMATOGRAPHY A, [PMID:38788322] [10.1016/j.chroma.2024.464991] |
| 21. Chun-Ying Xu, Yi-Xin Zhong, Yuan-Yuan Cui, Cheng-Xiong Yang. (2024) Thiol-yne click post-synthesis of phenylboronic acid-functionalized magnetic cyclodextrin microporous organic network for selective and efficient extraction of antiepileptic drugs. TALANTA, [PMID:38897013] [10.1016/j.talanta.2024.126440] |
| 22. Gu Chao-Hai, Wang Song, Zhang Ai-Yong, Liu Chang, Jiang Jun, Yu Han-Qing. (2024) Tuning electronic structure of metal-free dual-site catalyst enables exclusive singlet oxygen production and in-situ utilization. Nature Communications, 15 (1): (1-11). [PMID:38982107] [10.1038/s41467-024-50240-0] |
| 23. Jie Du, Zhijun An, Yufeng Hu, Xianliang Yi, Hao Zhou, Jingjing Zhan, Minghuo Wu. (2022) Identification and characterization of Fe3O4/peroxodisulfate advanced oxidation products from sulfameter. Journal of Environmental Sciences, [PMID:35717087] [10.1016/j.jes.2022.02.007] |
| 24. Wenming Yang, Xiangpeng Shi, Xiaoqiang Chen, Yuanzheng Cai, Yi Ji, Yunfei Cao, Wanzhen Xu. (2025) Multicolor Thioglycolic Acid-Modified CdTe Quantum Dot-Based Molecularly Imprinted Polymers for Highly Sensitive and Selective Detection of Sulfadiazine. POLYMERS FOR ADVANCED TECHNOLOGIES, 36 (11): (e70403). [PMID:] [10.1002/pat.70403] |
| 25. Jingfei Luan, Minghe Ma, Liang Hao, Hengchang Zeng, Anan Liu. (2025) Design and Synthesis of Dy2TmSbO7/BiHoO3 Heterojunction: The Mechanism and Application for Photocatalytic Degradation of Sulphamethoxypyridazine. MOLECULES, 31 (1): [PMID:41515321] [10.3390/molecules31010024] |
| 26. Jian-Ming Liu, Jian Liu, Tian-Tian Ma, Cheng-Xiong Yang. (2026) Post-esterification preparation of carboxyl groups enriched magnetic microporous organic network for the efficient enrichment and determination of quaternary ammonium alkaloids. ANALYTICA CHIMICA ACTA, [PMID:41698745] [10.1016/j.aca.2026.345173] |
| 27. Huiting Feng, Yuxin Yang, Ruiling Li, Yuting Yang, Zongwen Wang, FengFu Fu, Yue Lin. (2026) Employment of mixed aptamers and gold nanobipyramids toward a paper-based aptasensor for simultaneously visual screening and accurate detection of eight sulfonamides. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:] [10.1016/j.saa.2026.127574] |
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