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PKN1

DescriptionSerine/threonine-protein kinase N1

Gene and Protein Information

Gene ID5585
Uniprot Accession IDs Q16512 A8K7W5 B2R9R4 B3KVN3 Q15143 Q504U4 Q8IUV5 Q9UD44
Ensembl ID ENSP00000343325
Symbol PAK1 PKN PRK1 PRKCL1 DBK PKN PAK1 PRK1 PAK-1 PRKCL1 PKN-ALPHA
FamilyBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
Sequence
MASDAVQSEPRSWSLLEQLGLAGADLAAPGVQQQLELERERLRREIRKELKLKEGAENLRRATTDLGRSLGPVELLLRGSSRRLDLLHQQLQELHAHVVLPDPAATHDGPQSPGAGGPTCSATNLSRVAGLEKQLAIELKVKQGAENMIQTYSNGSTKDRKLLLTAQQMLQDSKTKIDIIRMQLRRALQAGQLENQAAPDDTQGSPDLGAVELRIEELRHHFRVEHAVAEGAKNVLRLLSAAKAPDRKAVSEAQEKLTESNQKLGLLREALERRLGELPADHPKGRLLREELAAASSAAFSTRLAGPFPATHYSTLCKPAPLTGTLEVRVVGCRDLPETIPWNPTPSMGGPGTPDSRPPFLSRPARGLYSRSGSLSGRSSLKAEAENTSEVSTVLKLDNTVVGQTSWKPCGPNAWDQSFTLELERARELELAVFWRDQRGLCALKFLKLEDFLDNERHEVQLDMEPQGCLVAEVTFRNPVIERIPRLRRQKKIFSKQQGKAFQRARQMNIDVATWVRLLRRLIPNATGTGTFSPGASPGSEARTTGDISVEKLNLGTDSDSSPQKSSRDPPSSPSSLSSPIQESTAPELPSETQETPGPALCSPLRKSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAIFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTLSPPRDARPLTAAEQAAFLDFDFVAGGC
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp455785PKN1protein kinase N19598VGNC:2286OMA, EggNOG
Macaque718834PKN1protein kinase N19544OMA, EggNOG
Mouse320795Pkn1protein kinase N110090MGI:108022Inparanoid, OMA, EggNOG
Rat29355Pkn1protein kinase N110116RGD:69308Inparanoid, OMA, EggNOG
Dog100856398PKN1protein kinase N19615VGNC:44611Inparanoid, OMA, EggNOG
Cow509080PKN1protein kinase N19913VGNC:32945Inparanoid, OMA, EggNOG
Opossum100026472PKN1protein kinase N113616Inparanoid, OMA, EggNOG
Anole lizard100566151pkn1protein kinase N128377Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    calcium-binding protein    /    non-receptor serine/threonine protein kinase    /    Serine/threonine-protein kinase n1
protein    /    calcium-binding protein    /    transfer/carrier protein    /    Serine/threonine-protein kinase n1
protein    /    calcium-binding protein    /    protein kinase    /    Serine/threonine-protein kinase n1
protein    /    calcium-binding protein    /    calmodulin    /    Serine/threonine-protein kinase n1
protein    /    calcium-binding protein    /    annexin    /    Serine/threonine-protein kinase n1
protein    /    calcium-binding protein    /    transferase    /    Serine/threonine-protein kinase n1
protein    /    calcium-binding protein    /    kinase    /    Serine/threonine-protein kinase n1
DTO Classes
protein    /    Kinase    /    Protein kinase    /    AGC group    /    PKN family    /    Serine/threonine-protein kinase n1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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