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PDGFRA

DescriptionPlatelet-derived growth factor receptor alpha

Gene and Protein Information

Gene ID5156
Uniprot Accession IDs P16234 B2RE69 E9PBH0 Q6P4H5 Q96KZ7 Q9UD28 PDGF-R-alpha
Ensembl ID ENSP00000257290
Symbol PDGFR2 RHEPDGFRA CD140A PDGFR2 PDGFR-2
FamilyBelongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Sequence
MGTSHPAFLVLGCLLTGLSLILCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYPMSEEESSDVEIRNEENNSGLFVTVLEVSSASAAHTGLYTCYYNHTQTEENELEGRHIYIYVPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVTLHNSEGVVPASYDSRQGFNGTFTVGPYICEATVKGKKFQTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNNEVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLTVPEATVKDSGDYECAARQATREVKEMKKVTISVHEKGFIEIKPTFSQLEAVNLHEVKHFVVEVRAYPPPRISWLKNNLTLIENLTEITTDVEKIQEIRYRSKLKLIRAKEEDSGHYTIVAQNEDAVKSYTFELLTQVPSSILDLVDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWTILANNVSNIITEIHSRDRSTVEGRVTFAKVEETIAVRCLAKNLLGAENRELKLVAPTLRSELTVAAAVLVLLVIVIISLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRVLGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSHHPEKPKKELDIFGLNPADESTRSYVILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKNLLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLPGQYKKSYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKDWEGGLDEQRLSADSGYIIPLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDSSDLVEDSFL
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp461318PDGFRAplatelet derived growth factor receptor alpha9598OMA, EggNOG
MacaquePDGFRAplatelet derived growth factor receptor alpha [Source:HGNC Symbol;Acc:HGNC:8803]9544Inparanoid, EggNOG
Mouse18595Pdgfraplatelet derived growth factor receptor, alpha polypeptide10090MGI:97530Inparanoid, OMA, EggNOG
Rat25267Pdgfraplatelet derived growth factor receptor alpha10116RGD:3284Inparanoid, OMA, EggNOG
Dog442860PDGFRAplatelet derived growth factor receptor alpha9615VGNC:44372Inparanoid, OMA, EggNOG
Horse100059815PDGFRAplatelet derived growth factor receptor alpha9796VGNC:21261Inparanoid, OMA, EggNOG
Cow282301PDGFRAplatelet derived growth factor receptor alpha9913VGNC:32692Inparanoid, OMA, EggNOG
Opossum100013088PDGFRAplatelet derived growth factor receptor alpha13616Inparanoid, OMA, EggNOG
Platypus100084432PDGFRAplatelet derived growth factor receptor alpha9258Inparanoid, OMA, EggNOG
Chicken395509PDGFRAplatelet-derived growth factor receptor, alpha polypeptide9031CGNC:10416Inparanoid, OMA, EggNOG
Anole lizard100565834pdgfraplatelet derived growth factor receptor alpha28377Inparanoid, OMA
Xenopus100124862pdgfraplatelet-derived growth factor receptor, alpha polypeptide8364XB-GENE-6072920Inparanoid, OMA, EggNOG
Zebrafish386856pdgfraplatelet-derived growth factor receptor, alpha polypeptide7955ZDB-GENE-990415-208Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TK group    /    PDGFR family    /    Platelet-derived growth factor receptor alpha

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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