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PLK1

DescriptionSerine/threonine-protein kinase PLK1

Gene and Protein Information

Gene ID5347
Uniprot Accession IDs P53350 Q15153 Q99746
Ensembl ID ENSP00000300093
Symbol PLK PLK STPK13
FamilyBelongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
Sequence
MSAAVTAGKLARAPADPGKAGVPGVAAPGAPAAAPPAKEIPEVLVDPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITCLTIPPRFSIAPSSLDPSNRKPLTVLNKGLENPLPERPREKEEPVVRETGEVVDCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSRSASNRLKAS
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp453991PLK1polo like kinase 19598VGNC:8992Inparanoid, OMA, EggNOG
Macaque697686PLK1polo like kinase 19544Inparanoid, EggNOG
Mouse18817Plk1polo like kinase 110090MGI:97621Inparanoid, OMA, EggNOG
Rat25515Plk1polo-like kinase 110116RGD:3352Inparanoid, OMA, EggNOG
Dog489971PLK1polo like kinase 19615VGNC:44695Inparanoid, OMA, EggNOG
Horse100068388PLK1polo like kinase 19796VGNC:21579Inparanoid, OMA, EggNOG
Cow538238PLK1polo like kinase 19913VGNC:33033Inparanoid, OMA, EggNOG
Pig396953PLK1polo like kinase 19823Inparanoid, OMA, EggNOG
Opossum100027403PLK1polo like kinase 113616Inparanoid, OMA, EggNOG
Platypus100073533PLK1polo like kinase 19258Inparanoid, OMA, EggNOG
Chicken416575PLK1polo like kinase 19031CGNC:4585Inparanoid, OMA, EggNOG
Anole lizard100558384plk1polo like kinase 128377Inparanoid, OMA, EggNOG
Xenopus407937plk1polo like kinase 18364XB-GENE-941540Inparanoid, OMA, EggNOG
Zebrafish280649plk1polo-like kinase 1 (Drosophila)7955ZDB-GENE-021115-7Inparanoid, OMA, EggNOG
C. elegans176143plk-1Serine/threonine-protein kinase plk-16239OMA, EggNOG
C. elegans171838plk-2Serine/threonine-protein kinase plk-26239Inparanoid, OMA
Fruitfly40232poloCG12306 gene product from transcript CG12306-RA7227FBgn0003124Inparanoid, OMA, EggNOG
S.cerevisiae855013CDC5polo kinase CDC54932S000004603OMA, EggNOG

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    Other group    /    PLK family    /    Serine/threonine-protein kinase plk1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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