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| Description | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A |
|---|
Gene and Protein Information
| Gene ID | 5151 |
|---|---|
| Uniprot Accession IDs | O60658 B3KXE6 H0YMZ7 Q6P9H3 Q969I1 Q96PC9 Q96PD0 Q96PD1 Q96T71 Q9UMB7 Q9UMC3 |
| Ensembl ID | ENSP00000311453 |
| Symbol | HsT19550 |
| Family | Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily. |
| Sequence | MGCAPSIHISERLVAEDAPSPAAPPLSSGGPRLPQGQKTAALPRTRGAGLLESELRDGSGKKVAVADVQFGPMRFHQDQLQVLLVFTKEDNQCNGFCRACEKAGFKCTVTKEAQAVLACFLDKHHDIIIIDHRNPRQLDAEALCRSIRSSKLSENTVIVGVVRRVDREELSVMPFISAGFTRRYVENPNIMACYNELLQLEFGEVRSQLKLRACNSVFTALENSEDAIEITSEDRFIQYANPAFETTMGYQSGELIGKELGEVPINEKKADLLDTINSCIRIGKEWQGIYYAKKKNGDNIQQNVKIIPVIGQGGKIRHYVSIIRVCNGNNKAEKISECVQSDTHTDNQTGKHKDRRKGSLDVKAVASRATEVSSQRRHSSMARIHSMTIEAPITKVINIINAAQESSPMPVTEALDRVLEILRTTELYSPQFGAKDDDPHANDLVGGLMSDGLRRLSGNEYVLSTKNTQMVSSNIITPISLDDVPPRIARAMENEEYWDFDIFELEAATHNRPLIYLGLKMFARFGICEFLHCSESTLRSWLQIIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIHDVDHPGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQGIIDMVLATEMTKHFEHVNKFVNSINKPLATLEENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFSQTDEEKQQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFVDLPDLMQHLDNNFKYWKGLDEMKLRNLRPPPE Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 453612 | PDE8A | phosphodiesterase 8A | 9598 | VGNC:1899 | OMA, EggNOG |
| Macaque | 694750 | PDE8A | phosphodiesterase 8A | 9544 | OMA, EggNOG | |
| Rat | 308776 | Pde8a | phosphodiesterase 8A | 10116 | RGD:735125 | OMA, EggNOG |
| Dog | 488752 | PDE8A | phosphodiesterase 8A | 9615 | VGNC:44365 | OMA, EggNOG |
| Horse | 100068475 | PDE8A | phosphodiesterase 8A | 9796 | VGNC:21256 | OMA, EggNOG |
| Cow | 506787 | PDE8A | phosphodiesterase 8A | 9913 | VGNC:32687 | OMA, EggNOG |
| Anole lizard | 100557720 | LOC100557720 | high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A | 28377 | OMA, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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