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| Description | Interferon-induced, double-stranded RNA-activated protein kinase |
|---|
Gene and Protein Information
| Gene ID | 5610 |
|---|---|
| Uniprot Accession IDs | P19525 A8K3P0 D6W584 E9PC80 Q52M43 Q7Z6F6 Q9UIR4 |
| Ensembl ID | ENSP00000233057 |
| Symbol | PKR PRKR PKR PRKR EIF2AK1 PPP1R83 |
| Family | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily. |
| Sequence | MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQCASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSGSFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAKRSLAPRFDLPDMKETKYTVDKRFGMDFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESSDYDPENSKNSSRSKTKCLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWKKSPEKNERHTC Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 459155 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 | 9598 | VGNC:235 | Inparanoid, OMA, EggNOG |
| Mouse | 19106 | Eif2ak2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 10090 | MGI:1353449 | Inparanoid, OMA, EggNOG |
| Rat | 54287 | Eif2ak2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 10116 | RGD:3402 | Inparanoid, OMA, EggNOG |
| Dog | 611397 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 | 9615 | VGNC:40257 | Inparanoid, OMA, EggNOG |
| Horse | 100147679 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 | 9796 | VGNC:17478 | Inparanoid, OMA, EggNOG |
| Cow | 347700 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 | 9913 | VGNC:28381 | Inparanoid, OMA, EggNOG |
| Platypus | 100077821 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 | 9258 | Inparanoid, OMA, EggNOG | |
| Chicken | 395147 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 | 9031 | CGNC:8018 | Inparanoid, OMA, EggNOG |
| Anole lizard | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 [Source:HGNC Symbol;Acc:HGNC:9437] | 28377 | Inparanoid, OMA, EggNOG | ||
| Xenopus | 779992 | eif2ak2 | eukaryotic translation initiation factor 2 alpha kinase 2 | 8364 | XB-GENE-1001011 | OMA, EggNOG |
| Zebrafish | 100001092 | eif2ak2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 7955 | ZDB-GENE-080422-1 | Inparanoid, OMA |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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