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MAP4K2

DescriptionMitogen-activated protein kinase kinase kinase kinase 2

Gene and Protein Information

Gene ID5871
Uniprot Accession IDs Q12851 Q86VU3
Ensembl ID ENSP00000294066
Symbol GCK RAB8IP GCK BL44 RAB8IP
FamilyBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Sequence
MALLRDVSLQDPRDRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDDISSLQQEITILRECRHPNVVAYIGSYLRNDRLWICMEFCGGGSLQEIYHATGPLEERQIAYVCREALKGLHHLHSQGKIHRDIKGANLLLTLQGDVKLADFGVSGELTASVAKRRSFIGTPYWMAPEVAAVERKGGYNELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSSFQPPKLRDKTRWTQNFHHFLKLALTKNPKKRPTAEKLLQHPFTTQQLPRALLTQLLDKASDPHLGTPSPEDCELETYDMFPDTIHSRGQHGPAERTPSEIQFHQVKFGAPRRKETDPLNEPWEEEWTLLGKEELSGSLLQSVQEALEERSLTIRSASEFQELDSPDDTMGTIKRAPFLGPLPTDPPAEEPLSSPPGTLPPPPSGPNSSPLLPTAWATMKQREDPERSSCHGLPPTPKVHMGACFSKVFNGCPLRIHAAVTWIHPVTRDQFLVVGAEEGIYTLNLHELHEDTLEKLISHRCSWLYCVNNVLLSLSGKSTHIWAHDLPGLFEQRRLQQQVPLSIPTNRLTQRIIPRRFALSTKIPDTKGCLQCRVVRNPYTGATFLLAALPTSLLLLQWYEPLQKFLLLKNFSSPLPSPAGMLEPLVLDGKELPQVCVGAEGPEGPGCRVLFHVLPLEAGLTPDILIPPEGIPGSAQQVIQVDRDTILVSFERCVRIVNMQGEPTATLAPELTFDFPIETVVCLQDSVLAFWSHGMQGRSLDTNEVTQEITDETRIFRVLGAHRDIILESIPTDNPEAHSNLYILTGHQSTY
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp451301MAP4K2mitogen-activated protein kinase kinase kinase kinase 29598VGNC:7507OMA, EggNOG
Macaque699331MAP4K2mitogen-activated protein kinase kinase kinase kinase 29544OMA, EggNOG
Mouse26412Map4k2mitogen-activated protein kinase kinase kinase kinase 210090MGI:1346883Inparanoid, OMA, EggNOG
Rat293694Map4k2mitogen activated protein kinase kinase kinase kinase 210116RGD:1308199Inparanoid, OMA
Dog483759MAP4K2mitogen-activated protein kinase kinase kinase kinase 29615VGNC:42982Inparanoid, OMA
Horse100056001MAP4K2mitogen-activated protein kinase kinase kinase kinase 29796VGNC:19946Inparanoid, OMA
Cow520058MAP4K2mitogen-activated protein kinase kinase kinase kinase 29913VGNC:31205Inparanoid, OMA
Pig100523716MAP4K2mitogen-activated protein kinase kinase kinase kinase 29823Inparanoid, OMA
C. elegans179072gck-2Mitogen-activated protein kinase kinase kinase kinase6239Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    STE group    /    STE20 family    /    KHS subfamily    /    Mitogen-activated protein kinase kinase kinase kinase 2

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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