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GAA

DescriptionLysosomal alpha-glucosidase

Gene and Protein Information

Gene ID2548
Uniprot Accession IDs P10253 Q09GN4 Q14351 Q16302 Q8IWE7
Ensembl ID ENSP00000305692
Symbol LYAG
FamilyBelongs to the glycosyl hydrolase 31 family.
Sequence
MGVRHPPCSHRLLAVCALVSLATAALLGHILLHDFLLVPRELSGSSPVLEETHPAHQQGASRPGPRDAQAHPGRPRAVPTQCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFPPSYPSYKLENLSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETPHVHSRAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLEVLERGAYTQVIFLARNNTIVNELVRVTSEGAGLQLQKVTVLGVATAPQQVLSNGVPVSNFTYSPDTKVLDICVSLLMGEQFLVSWC
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp454940GAAglucosidase alpha, acid9598VGNC:9298OMA, EggNOG
Macaque712054GAAglucosidase alpha, acid9544Inparanoid, OMA, EggNOG
Mouse14387Gaaglucosidase, alpha, acid10090MGI:95609Inparanoid, OMA, EggNOG
Rat367562Gaaglucosidase, alpha, acid10116RGD:735227Inparanoid, OMA, EggNOG
Dog483352GAAglucosidase alpha, acid9615VGNC:41044Inparanoid, OMA, EggNOG
Horse100056675GAAglucosidase alpha, acid9796VGNC:18184Inparanoid, OMA, EggNOG
Cow280798GAAglucosidase alpha, acid9913VGNC:29182Inparanoid, OMA, EggNOG
Pig100526132GAAglucosidase alpha, acid9823OMA, EggNOG
Opossum100030818GAAglucosidase alpha, acid13616Inparanoid, OMA, EggNOG
PlatypusGAAglucosidase alpha, acid [Source:HGNC Symbol;Acc:HGNC:4065]9258OMA, EggNOG
Anole lizard100561813gaaglucosidase alpha, acid28377Inparanoid, OMA
Xenopusgaaglucosidase, alpha; acid [Source:Xenbase;Acc:XB-GENE-6054131]8364OMA, EggNOG
Zebrafish100002366gaaglucosidase, alpha; acid (Pompe disease, glycogen storage disease type II)7955ZDB-GENE-070212-2Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    hydrolase    /    glucosidase    /    Lysosomal alpha-glucosidase
DTO Classes
protein    /    Enzyme    /    Hydrolase    /    Glucosidase    /    Lysosomal alpha-glucosidase

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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