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| Description | Mitogen-activated protein kinase kinase kinase 12 |
|---|
Gene and Protein Information
| Gene ID | 7786 |
|---|---|
| Uniprot Accession IDs | Q12852 B3KSS9 G3V1Y2 Q86VQ5 Q8WY25 |
| Ensembl ID | ENSP00000448689 |
| Symbol | ZPK DLK MUK ZPK ZPKP1 MEKK12 |
| Family | Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. |
| Sequence | MACLHETRTPSPSFGGFVSTLSEASMRKLDPDTSDCTPEKDLTPTHVLQLHEQDAGGPGGAAGSPESRASRVRADEVRLQCQSGSGFLEGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRFHGEEVAVKKVRDLKETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQETYFKSQAEWREEVKLHFEKIKSEGTCLHRLEEELVMRRREELRHALDIREHYERKLERANNLYMELNALMLQLELKERELLRREQALERRCPGLLKPHPSRGLLHGNTMEKLIKKRNVPQKLSPHSKRPDILKTESLLPKLDAALSGVGLPGCPKGPPSPGRSRRGKTRHRKASAKGSCGDLPGLRTAVPPHEPGGPGSPGGLGGGPSAWEACPPALRGLHHDLLLRKMSSSSPDLLSAALGSRGRGATGGAGDPGSPPPARGDTPPSEGSAPGSTSPDSPGGAKGEPPPPVGPGEGVGLLGTGREGTSGRGGSRAGSQHLTPAALLYRAAVTRSQKRGISSEEEEGEVDSEVELTSSQRWPQSLNMRQSLSTFSSENPSDGEEGTASEPSPSGTPEVGSTNTDERPDERSDDMCSQGSEIPLDPPPSEVIPGPEPSSLPIPHQELLRERGPPNSEDSDCDSTELDNSNSVDALRPPASLPP Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 451940 | MAP3K12 | mitogen-activated protein kinase kinase kinase 12 | 9598 | VGNC:13213 | OMA, EggNOG |
| Macaque | 703059 | MAP3K12 | mitogen-activated protein kinase kinase kinase 12 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 26404 | Map3k12 | mitogen-activated protein kinase kinase kinase 12 | 10090 | MGI:1346881 | Inparanoid, OMA, EggNOG |
| Rat | 25579 | Map3k12 | mitogen activated protein kinase kinase kinase 12 | 10116 | RGD:3988 | Inparanoid, OMA, EggNOG |
| Dog | 607170 | MAP3K12 | mitogen-activated protein kinase kinase kinase 12 | 9615 | VGNC:42968 | Inparanoid, OMA |
| Horse | 100064002 | MAP3K12 | mitogen-activated protein kinase kinase kinase 12 | 9796 | VGNC:19931 | Inparanoid, OMA |
| Cow | 505427 | MAP3K12 | mitogen-activated protein kinase kinase kinase 12 | 9913 | VGNC:31190 | Inparanoid, OMA |
| Pig | 100517714 | MAP3K12 | mitogen-activated protein kinase kinase kinase 12 | 9823 | Inparanoid, OMA | |
| Anole lizard | 100553164 | map3k12 | mitogen-activated protein kinase kinase kinase 12 | 28377 | Inparanoid, OMA | |
| Xenopus | 100488307 | map3k12 | mitogen-activated protein kinase kinase kinase 12 | 8364 | XB-GENE-482768 | Inparanoid, OMA |
| Zebrafish | 404626 | map3k12 | mitogen-activated protein kinase kinase kinase 12 | 7955 | ZDB-GENE-040426-2436 | Inparanoid, OMA |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / TKL group / MLK family / Mitogen-activated protein kinase kinase kinase 12
protein / Kinase / Protein kinase / TKL group / MLK family / Mitogen-activated protein kinase kinase kinase 12
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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