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MAP3K2

DescriptionMitogen-activated protein kinase kinase kinase 2

Gene and Protein Information

Gene ID10746
Uniprot Accession IDs Q9Y2U5 B9EG87 Q53QL9 Q53S75 Q59GZ6 Q8NC32 Q9NYK3
Ensembl ID ENSP00000387246
Symbol MAPKKK2 MEKK2 MEKK2 MEKK2B
FamilyBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Sequence
MDDQQALNSIMQDLAVLHKASRPALSLQETRKAKSSSPKKQNDVRVKFEHRGEKRILQFPRPVKLEDLRSKAKIAFGQSMDLHYTNNELVIPLTTQDDLDKAVELLDRSIHMKSLKILLVINGSTQATNLEPLPSLEDLDNTVFGAERKKRLSIIGPTSRDRSSPPPGYIPDELHQVARNGSFTSINSEGEFIPESMDQMLDPLSLSSPENSGSGSCPSLDSPLDGESYPKSRMPRAQSYPDNHQEFSDYDNPIFEKFGKGGTYPRRYHVSYHHQEYNDGRKTFPRARRTQGTSLRSPVSFSPTDHSLSTSSGSSIFTPEYDDSRIRRRGSDIDNPTLTVMDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKLPPHVSDYTRDFLKRIFVEAKLRPSADELLRHMFVHYH
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp736244MAP3K2mitogen-activated protein kinase kinase kinase 29598VGNC:14152OMA, EggNOG
Macaque100424131MAP3K2mitogen-activated protein kinase kinase kinase 29544OMA, EggNOG
Mouse26405Map3k2mitogen-activated protein kinase kinase kinase 210090MGI:1346873Inparanoid, OMA, EggNOG
Rat171492Map3k2mitogen activated protein kinase kinase kinase 210116RGD:620967Inparanoid, OMA, EggNOG
Dog612902MAP3K2mitogen-activated protein kinase kinase kinase 29615VGNC:42972Inparanoid, OMA
Horse100050628MAP3K2mitogen-activated protein kinase kinase kinase 29796VGNC:19936Inparanoid, OMA
Pig100621234MAP3K2mitogen-activated protein kinase kinase kinase 29823Inparanoid, OMA
Opossum100026735MAP3K2mitogen-activated protein kinase kinase kinase 213616Inparanoid, OMA
Chicken424225MAP3K2mitogen-activated protein kinase kinase kinase 29031CGNC:8740Inparanoid, OMA
Anole lizard100558170map3k2mitogen-activated protein kinase kinase kinase 228377Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    STE group    /    STE11 family    /    Mitogen-activated protein kinase kinase kinase 2

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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