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| Description | Mitogen-activated protein kinase kinase kinase 3 |
|---|
Gene and Protein Information
| Gene ID | 4215 |
|---|---|
| Uniprot Accession IDs | Q99759 B2RCW2 D3DU15 Q5BKZ6 Q8N3I9 |
| Ensembl ID | ENSP00000354927 |
| Symbol | MAPKKK3 MEKK3 MEKK3 MAPKKK3 |
| Family | Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. |
| Sequence | MDEQEALNSIMNDLVALQMNRRHRMPGYETMKNKDTGHSNRQSDVRIKFEHNGERRIIAFSRPVKYEDVEHKVTTVFGQPLDLHYMNNELSILLKNQDDLDKAIDILDRSSSMKSLRILLLSQDRNHNSSSPHSGVSRQVRIKASQSAGDINTIYQPPEPRSRHLSVSSQNPGRSSPPPGYVPERQQHIARQGSYTSINSEGEFIPETSEQCMLDPLSSAENSLSGSCQSLDRSADSPSFRKSRMSRAQSFPDNRQEYSDRETQLYDKGVKGGTYPRRYHVSVHHKDYSDGRRTFPRIRRHQGNLFTLVPSSRSLSTNGENMGLAVQYLDPRGRLRSADSENALSVQERNVPTKSPSAPINWRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPSHISEHGRDFLRRIFVEARQRPSAEELLTHHFAQLMY Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 468286 | MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | 9598 | VGNC:9367 | OMA, EggNOG |
| Macaque | 717866 | MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 26406 | Map3k3 | mitogen-activated protein kinase kinase kinase 3 | 10090 | MGI:1346874 | Inparanoid, OMA, EggNOG |
| Rat | 303604 | Map3k3 | mitogen activated protein kinase kinase kinase 3 | 10116 | RGD:1304575 | Inparanoid, OMA |
| Dog | 480481 | MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | 9615 | VGNC:42973 | Inparanoid, OMA, EggNOG |
| Horse | 100064751 | MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | 9796 | VGNC:19937 | Inparanoid, OMA, EggNOG |
| Cow | 508943 | MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | 9913 | VGNC:31196 | Inparanoid, OMA, EggNOG |
| Pig | 100513491 | MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100025970 | MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | 13616 | Inparanoid, OMA, EggNOG | |
| Chicken | 419954 | MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | 9031 | CGNC:323 | Inparanoid, OMA |
| Anole lizard | 100557698 | map3k3 | mitogen-activated protein kinase kinase kinase 3 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | XB-GENE-986927 | Putative ortholog of mitogen-activated protein kinase kinase kinase 3 (EC 2.7.1.37) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3), 1 of 1 [Source:Xenbase;Acc:XB-GENE-986927] | 8364 | OMA, EggNOG | ||
| Zebrafish | 560211 | map3k3 | mitogen-activated protein kinase kinase kinase 3 | 7955 | ZDB-GENE-070910-1 | Inparanoid, OMA, EggNOG |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / STE group / STE11 family / Mitogen-activated protein kinase kinase kinase 3
protein / Kinase / Protein kinase / STE group / STE11 family / Mitogen-activated protein kinase kinase kinase 3
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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