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| Description | DNA mismatch repair protein Mlh1 |
|---|
Gene and Protein Information
| Gene ID | 4292 |
|---|---|
| Uniprot Accession IDs | P40692 B4DI13 B4DQ11 E9PCU2 |
| Ensembl ID | ENSP00000231790 |
| Symbol | COCA2 FCC2 COCA2 HNPCC hMLH1 HNPCC2 |
| Family | Belongs to the DNA mismatch repair MutL/HexB family. |
| Sequence | MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDNGTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTADGKCAYRASYSDGKLKAPPKPCAGNQGTQITVEDLFYNIATRRKALKNPSEEYGKILEVVGRYSVHNAGISFSVKKQGETVADVRTLPNASTVDNIRSIFGNAVSRELIEIGCEDKTLAFKMNGYISNANYSVKKCIFLLFINHRLVESTSLRKAIETVYAAYLPKNTHPFLYLSLEISPQNVDVNVHPTKHEVHFLHEESILERVQQHIESKLLGSNSSRMYFTQTLLPGLAGPSGEMVKSTTSLTSSSTSGSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQAIVTEDKTDISSGRARQQDEEMLELPAPAEVAAKNQSLEGDTTKGTSEMSEKRGPTSSNPRKRHREDSDVEMVEDDSRKEMTAACTPRRRIINLTSVLSLQEEINEQGHEVLREMLHNHSFVGCVNPQWALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWTEEDGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEEGNLIGLPLLIDNYVPPLEGLPIFILRLATEVNWDEEKECFESLSKECAMFYSIRKQYISEESTLSGQQSEVPGSIPNSWKWTVEHIVYKALRSHILPPKHFTEDGNILQLANLPDLYKVFERC Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 747104 | MLH1 | mutL homolog 1 | 9598 | VGNC:2049 | OMA, EggNOG |
| Macaque | 698782 | MLH1 | mutL homolog 1 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 17350 | Mlh1 | mutL homolog 1 | 10090 | MGI:101938 | Inparanoid, OMA, EggNOG |
| Rat | 81685 | Mlh1 | mutL homolog 1 | 10116 | RGD:620937 | Inparanoid, OMA, EggNOG |
| Dog | 477019 | MLH1 | mutL homolog 1 | 9615 | VGNC:43257 | Inparanoid, OMA, EggNOG |
| Horse | 100050351 | MLH1 | mutL homolog 1 | 9796 | VGNC:20209 | Inparanoid, OMA, EggNOG |
| Cow | 533652 | MLH1 | mutL homolog 1 | 9913 | VGNC:31497 | Inparanoid, OMA, EggNOG |
| Pig | 100337665 | MLH1 | mutL homolog 1 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100011682 | MLH1 | mutL homolog 1 | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | MLH1 | mutL homolog 1 [Source:HGNC Symbol;Acc:HGNC:7127] | 9258 | OMA, EggNOG | ||
| Anole lizard | 100555611 | mlh1 | mutL homolog 1 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | MLH1 | mutL homolog 1 [Source:HGNC Symbol;Acc:HGNC:7127] | 8364 | OMA, EggNOG | ||
| Zebrafish | 393632 | mlh1 | mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) | 7955 | ZDB-GENE-040426-1600 | Inparanoid, OMA, EggNOG |
| C. elegans | 176783 | mlh-1 | MLH (MutL Homolog) family | 6239 | Inparanoid, OMA | |
| Fruitfly | 35796 | Mlh1 | CG11482 gene product from transcript CG11482-RB | 7227 | FBgn0011659 | Inparanoid, EggNOG |
| S.cerevisiae | 855203 | MLH1 | mismatch repair ATPase MLH1 | 4932 | S000004777 | Inparanoid, OMA, EggNOG |
Protein Classes
PANTHER Classes
protein / nucleic acid binding / DNA binding protein / DNA mismatch repair protein Mlh1
protein / nucleic acid binding / DNA binding protein / DNA mismatch repair protein Mlh1
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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