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ABCC5

DescriptionMultidrug resistance-associated protein 5

Gene and Protein Information

Gene ID10057
Uniprot Accession IDs O15440 B9EIQ2 O14517 Q29ZA9 Q29ZB1 Q86UX3 Q86W30 Q9UN85 Q9UNP5 Q9UQC3
Ensembl ID ENSP00000333926
Symbol MRP5 MRP5 SMRP ABC33 MOATC MOAT-C pABC11 EST277145
FamilyBelongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Sequence
MKDIDIGKEYIIPSPGYRSVRERTSTSGTHRDREDSKFRRTRPLECQDALETAARAEGLSLDASMHSQLRILDEEHPKGKYHHGLSALKPIRTTSKHQHPVDNAGLFSCMTFSWLSSLARVAHKKGELSMEDVWSLSKHESSDVNCRRLERLWQEELNEVGPDAASLRRVVWIFCRTRLILSIVCLMITQLAGFSGPAFMVKHLLEYTQATESNLQYSLLLVLGLLLTEIVRSWSLALTWALNYRTGVRLRGAILTMAFKKILKLKNIKEKSLGELINICSNDGQRMFEAAAVGSLLAGGPVVAILGMIYNVIILGPTGFLGSAVFILFYPAMMFASRLTAYFRRKCVAATDERVQKMNEVLTYIKFIKMYAWVKAFSQSVQKIREEERRILEKAGYFQSITVGVAPIVVVIASVVTFSVHMTLGFDLTAAQAFTVVTVFNSMTFALKVTPFSVKSLSEASVAVDRFKSLFLMEEVHMIKNKPASPHIKIEMKNATLAWDSSHSSIQNSPKLTPKMKKDKRASRGKKEKVRQLQRTEHQAVLAEQKGHLLLDSDERPSPEEEEGKHIHLGHLRLQRTLHSIDLEIQEGKLVGICGSVGSGKTSLISAILGQMTLLEGSIAISGTFAYVAQQAWILNATLRDNILFGKEYDEERYNSVLNSCCLRPDLAILPSSDLTEIGERGANLSGGQRQRISLARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKHLKSKTVLFVTHQLQYLVDCDEVIFMKEGCITERGTHEELMNLNGDYATIFNNLLLGETPPVEINSKKETSGSQKKSQDKGPKTGSVKKEKAVKPEEGQLVQLEEKGQGSVPWSVYGVYIQAAGGPLAFLVIMALFMLNVGSTAFSTWWLSYWIKQGSGNTTVTRGNETSVSDSMKDNPHMQYYASIYALSMAVMLILKAIRGVVFVKGTLRASSRLHDELFRRILRSPMKFFDTTPTGRILNRFSKDMDEVDVRLPFQAEMFIQNVILVFFCVGMIAGVFPWFLVAVGPLVILFSVLHIVSRVLIRELKRLDNITQSPFLSHITSSIQGLATIHAYNKGQEFLHRYQELLDDNQAPFFLFTCAMRWLAVRLDLISIALITTTGLMIVLMHGQIPPAYAGLAISYAVQLTGLFQFTVRLASETEARFTSVERINHYIKTLSLEAPARIKNKAPSPDWPQEGEVTFENAEMRYRENLPLVLKKVSFTIKPKEKIGIVGRTGSGKSSLGMALFRLVELSGGCIKIDGVRISDIGLADLRSKLSIIPQEPVLFSGTVRSNLDPFNQYTEDQIWDALERTHMKECIAQLPLKLESEVMENGDNFSVGERQLLCIARALLRHCKILILDEATAAMDTETDLLIQETIREAFADCTMLTIAHRLHTVLGSDRIMVLAQGQVVEFDTPSVLLSNDSSRFYAMFAAAENKVAVKG
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Macaque704326ABCC5ATP binding cassette subfamily C member 59544Inparanoid, OMA, EggNOG
Mouse27416Abcc5ATP-binding cassette, sub-family C (CFTR/MRP), member 510090MGI:1351644Inparanoid, OMA, EggNOG
Rat116721Abcc5ATP binding cassette subfamily C member 510116RGD:70913Inparanoid, OMA, EggNOG
Dog478648ABCC5ATP binding cassette subfamily C member 59615VGNC:37442Inparanoid, OMA, EggNOG
Horse100066941ABCC5ATP binding cassette subfamily C member 59796VGNC:14920Inparanoid, OMA, EggNOG
Cow511769ABCC5ATP binding cassette subfamily C member 59913VGNC:25474OMA, EggNOG
Pig100513626ABCC5ATP binding cassette subfamily C member 59823OMA, EggNOG
Opossum100011713ABCC5ATP binding cassette subfamily C member 513616Inparanoid, OMA, EggNOG
Platypus100073452ABCC5ATP binding cassette subfamily C member 59258Inparanoid, OMA, EggNOG
Chicken424947ABCC5ATP binding cassette subfamily C member 59031CGNC:6342Inparanoid, EggNOG
Anole lizard100566117abcc5ATP binding cassette subfamily C member 528377Inparanoid, OMA, EggNOG
Zebrafish336147abcc5ATP-binding cassette, sub-family C (CFTR/MRP), member 57955ZDB-GENE-050517-17Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    transporter    /    ATP-binding cassette (ABC) transporter    /    Multidrug resistance-associated protein 5
DTO Classes
protein    /    Transporter    /    ATP-binding cassette transporter family    /    ABCC subfamily    /    Multidrug resistance-associated protein 5

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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