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ABCC4

DescriptionMultidrug resistance-associated protein 4

Gene and Protein Information

Gene ID10257
Uniprot Accession IDs O15439 A9Z1Z7 B7Z3Q7 Q8IVZ4 Q8IZN6 Q8NEW8 Q9Y6J2
Ensembl ID ENSP00000366084
Symbol MRP4 MRP4 MOATB MOAT-B
FamilyBelongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Sequence
MLPVYQEVKPNPLQDANLCSRVFFWWLNPLFKIGHKRRLEEDDMYSVLPEDRSQHLGEELQGFWDKEVLRAENDAQKPSLTRAIIKCYWKSYLVLGIFTLIEESAKVIQPIFLGKIINYFENYDPMDSVALNTAYAYATVLTFCTLILAILHHLYFYHVQCAGMRLRVAMCHMIYRKALRLSNMAMGKTTTGQIVNLLSNDVNKFDQVTVFLHFLWAGPLQAIAVTALLWMEIGISCLAGMAVLIILLPLQSCFGKLFSSLRSKTATFTDARIRTMNEVITGIRIIKMYAWEKSFSNLITNLRKKEISKILRSSCLRGMNLASFFSASKIIVFVTFTTYVLLGSVITASRVFVAVTLYGAVRLTVTLFFPSAIERVSEAIVSIRRIQTFLLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKSGIDFGSLLKKDNEESEQPPVPGTPTLRNRTFSESSVWSQQSSRPSLKDGALESQDTENVPVTLSEENRSEGKVGFQAYKNYFRAGAHWIVFIFLILLNTAAQVAYVLQDWWLSYWANKQSMLNVTVNGGGNVTEKLDLNWYLGIYSGLTVATVLFGIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRILNRFSKDIGHLDDLLPLTFLDFIQTLLQVVGVVSVAVAVIPWIAIPLVPLGIIFIFLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAMFVIIVAFGSLILAKTLDAGQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVIEYTDLEKEAPWEYQKRPPPAWPHEGVIIFDNVNFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQLKETIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYVLLQNKESLFYKMVQQLGKAEAAALTETAKQVYFKRNYPHIGHTDHMVTNTSNGQPSTLTIFETAL
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp452625ABCC4ATP binding cassette subfamily C member 49598VGNC:13060OMA, EggNOG
Macaque695407LOC695407multidrug resistance-associated protein 49544OMA, EggNOG
Mouse239273Abcc4ATP-binding cassette, sub-family C (CFTR/MRP), member 410090MGI:2443111Inparanoid, OMA, EggNOG
Rat170924Abcc4ATP binding cassette subfamily C member 410116RGD:620266Inparanoid, OMA, EggNOG
Dog485523ABCC4ATP binding cassette subfamily C member 49615VGNC:37441Inparanoid, OMA, EggNOG
Horse100050431ABCC4ATP binding cassette subfamily C member 49796VGNC:14919Inparanoid, OMA, EggNOG
Cow515333LOC515333multidrug resistance-associated protein 49913OMA, EggNOG
Pig100738425LOC100738425multidrug resistance-associated protein 49823OMA, EggNOG
Opossum100027089ABCC4ATP binding cassette subfamily C member 413616Inparanoid, OMA, EggNOG
PlatypusABCC4ATP binding cassette subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:55]9258OMA, EggNOG
Chicken418791ABCC4ATP binding cassette subfamily C member 49031CGNC:12680Inparanoid, OMA, EggNOG
Anole lizard100558731abcc4ATP binding cassette subfamily C member 428377Inparanoid, OMA, EggNOG
Xenopusabcc4ATP binding cassette subfamily C member 4 [Source:Xenbase;Acc:XB-GENE-957302]8364OMA, EggNOG
Zebrafish368620abcc4ATP-binding cassette, sub-family C (CFTR/MRP), member 47955ZDB-GENE-030616-511Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    transporter    /    ATP-binding cassette (ABC) transporter    /    Multidrug resistance-associated protein 4
DTO Classes
protein    /    Transporter    /    ATP-binding cassette transporter family    /    ABCC subfamily    /    Multidrug resistance-associated protein 4

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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