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| Description | Dual specificity mitogen-activated protein kinase kinase 4 |
|---|
Gene and Protein Information
| Gene ID | 6416 |
|---|---|
| Uniprot Accession IDs | P45985 B2R7N7 B3KYB2 D3DTS5 Q5U0B8 Q6FHX4 Q6P9H2 Q6PIE6 MAP kinase kinase 4 |
| Ensembl ID | ENSP00000410402 |
| Symbol | JNKK1 MEK4 MKK4 PRKMK4 SEK1 SERK1 SKK1 JNKK MEK4 MKK4 SEK1 SKK1 JNKK1 SERK1 MAPKK4 PRKMK4 SAPKK1 SAPKK-1 |
| Family | Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily. |
| Sequence | MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGKRKALKLNFANPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 455065 | MAP2K4 | mitogen-activated protein kinase kinase 4 | 9598 | VGNC:9364 | OMA, EggNOG |
| Macaque | 718155 | MAP2K4 | mitogen-activated protein kinase kinase 4 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 26398 | Map2k4 | mitogen-activated protein kinase kinase 4 | 10090 | MGI:1346869 | Inparanoid, OMA, EggNOG |
| Rat | 287398 | Map2k4 | mitogen activated protein kinase kinase 4 | 10116 | RGD:1307040 | Inparanoid, OMA, EggNOG |
| Dog | 489508 | MAP2K4 | mitogen-activated protein kinase kinase 4 | 9615 | VGNC:42962 | Inparanoid, OMA, EggNOG |
| Horse | 100073094 | MAP2K4 | mitogen-activated protein kinase kinase 4 | 9796 | VGNC:19927 | Inparanoid, OMA, EggNOG |
| Cow | 526469 | MAP2K4 | mitogen-activated protein kinase kinase 4 | 9913 | VGNC:31185 | Inparanoid, OMA, EggNOG |
| Pig | 100520100 | MAP2K4 | mitogen-activated protein kinase kinase 4 | 9823 | OMA, EggNOG | |
| Opossum | 100019828 | MAP2K4 | mitogen-activated protein kinase kinase 4 | 13616 | Inparanoid, OMA, EggNOG | |
| Anole lizard | 100556629 | map2k4 | mitogen-activated protein kinase kinase 4 | 28377 | OMA, EggNOG | |
| Xenopus | 100135013 | map2k4 | mitogen-activated protein kinase kinase 4 | 8364 | XB-GENE-482151 | Inparanoid, OMA, EggNOG |
| Zebrafish | 403052 | map2k4a | mitogen-activated protein kinase kinase 4a | 7955 | ZDB-GENE-060512-98 | Inparanoid, OMA |
| C. elegans | 185682 | mkk-4 | MAP kinase kinase mkk-4 | 6239 | OMA, EggNOG | |
| Fruitfly | 41020 | Mkk4 | MAP kinase kinase 4 | 7227 | FBgn0024326 | Inparanoid, EggNOG |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / STE group / STE7 family / Dual specificity mitogen-activated protein kinase kinase 4
protein / Kinase / Protein kinase / STE group / STE7 family / Dual specificity mitogen-activated protein kinase kinase 4
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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