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CASR

DescriptionExtracellular calcium-sensing receptor

Gene and Protein Information

Gene ID846
Uniprot Accession IDs P41180 Q13912 Q16108 Q16109 Q16110 Q16379 Q2M1T0 Q4PJ19 CaR
Ensembl ID ENSP00000420194
Symbol GPRC2A PCAR1 CAR FHH FIH HHC EIG8 HHC1 NSHPT PCAR1 hCasR GPRC2A HYPOC1
FamilyBelongs to the G-protein coupled receptor 3 family.
Sequence
MAFYSCCWVLLALTWHTSAYGPDQRAQKKGDIILGGLFPIHFGVAAKDQDLKSRPESVECIRYNFRGFRWLQAMIFAIEEINSSPALLPNLTLGYRIFDTCNTVSKALEATLSFVAQNKIDSLNLDEFCNCSEHIPSTIAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLLSNKNQFKSFLRTIPNDEHQATAMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEERDICIDFSELISQYSDEEEIQHVVEVIQNSTAKVIVVFSSGPDLEPLIKEIVRRNITGKIWLASEAWASSSLIAMPQYFHVVGGTIGFALKAGQIPGFREFLKKVHPRKSVHNGFAKEFWEETFNCHLQEGAKGPLPVDTFLRGHEESGDRFSNSSTAFRPLCTGDENISSVETPYIDYTHLRISYNVYLAVYSIAHALQDIYTCLPGRGLFTNGSCADIKKVEAWQVLKHLRHLNFTNNMGEQVTFDECGDLVGNYSIINWHLSPEDGSIVFKEVGYYNVYAKKGERLFINEEKILWSGFSREVPFSNCSRDCLAGTRKGIIEGEPTCCFECVECPDGEYSDETDASACNKCPDDFWSNENHTSCIAKEIEFLSWTEPFGIALTLFAVLGIFLTAFVLGVFIKFRNTPIVKATNRELSYLLLFSLLCCFSSSLFFIGEPQDWTCRLRQPAFGISFVLCISCILVKTNRVLLVFEAKIPTSFHRKWWGLNLQFLLVFLCTFMQIVICVIWLYTAPPSSYRNQELEDEIIFITCHEGSLMALGFLIGYTCLLAAICFFFAFKSRKLPENFNEAKFITFSMLIFFIVWISFIPAYASTYGKFVSAVEVIAILAASFGLLACIFFNKIYIILFKPSRNTIEEVRCSTAAHAFKVAARATLRRSNVSRKRSSSLGGSTGSTPSSSISSKSNSEDPFPQPERQKQQQPLALTQQEQQQQPLTLPQQQRSQQQPRCKQKVIFGSGTVTFSLSFDEPQKNAMAHRNSTHQNSLEAQKSSDTLTRHEPLLPLQCGETDLDLTVQETGLQGPVGGDQRPEVEDPEELSPALVVSSSQSFVISGGGSTVTENVVNS
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp460628CASRcalcium sensing receptor9598VGNC:7031OMA, EggNOG
Macaque714441CASRcalcium sensing receptor9544Inparanoid, OMA, EggNOG
Mouse12374Casrcalcium-sensing receptor10090MGI:1351351Inparanoid, OMA, EggNOG
Rat24247Casrcalcium-sensing receptor10116RGD:2277Inparanoid, OMA, EggNOG
Dog488007CASRcalcium sensing receptor9615VGNC:38740Inparanoid, OMA, EggNOG
Horse100034084CASRcalcium sensing receptor9796VGNC:16075Inparanoid, OMA, EggNOG
Cow281038CASRcalcium sensing receptor9913VGNC:26788Inparanoid, OMA, EggNOG
Pig100520980CASRcalcium sensing receptor9823OMA, EggNOG
Opossum100018274CASRcalcium sensing receptor13616Inparanoid, OMA, EggNOG
PlatypusCASRcalcium sensing receptor [Source:HGNC Symbol;Acc:HGNC:1514]9258OMA, EggNOG
Anole lizard100561507casrcalcium sensing receptor28377Inparanoid, OMA, EggNOG
Xenopuscasrcalcium-sensing receptor [Source:Xenbase;Acc:XB-GENE-6065247]8364OMA, EggNOG
Zebrafish560607casrcalcium-sensing receptor7955ZDB-GENE-050119-8OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    receptor    /    ligand-gated ion channel    /    Extracellular calcium-sensing receptor
protein    /    receptor    /    ion channel    /    Extracellular calcium-sensing receptor
protein    /    receptor    /    G-protein coupled receptor    /    Extracellular calcium-sensing receptor
protein    /    receptor    /    ionotropic glutamate receptor    /    Extracellular calcium-sensing receptor
DTO Classes
protein    /    G-protein coupled receptor    /    Class C metabotropic glutamate/pheromone    /    Calcium-sensing receptor    /    Extracellular calcium-sensing receptor

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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