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| Description | Serine/threonine-protein kinase B-raf |
|---|
Gene and Protein Information
| Gene ID | 673 |
|---|---|
| Uniprot Accession IDs | P15056 A4D1T4 B6HY61 B6HY62 B6HY63 B6HY64 B6HY65 B6HY66 Q13878 Q3MIN6 Q9UDP8 Q9Y6T3 |
| Ensembl ID | ENSP00000288602 |
| Symbol | BRAF1 RAFB1 NS7 B-raf BRAF1 RAFB1 B-RAF1 |
| Family | Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. |
| Sequence | MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGAFPVH Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 463781 | BRAF | B-Raf proto-oncogene, serine/threonine kinase | 9598 | VGNC:14003 | OMA, EggNOG |
| Mouse | 109880 | Braf | Braf transforming gene | 10090 | MGI:88190 | Inparanoid, OMA, EggNOG |
| Rat | 114486 | Braf | B-Raf proto-oncogene, serine/threonine kinase | 10116 | RGD:619908 | Inparanoid, OMA, EggNOG |
| Dog | 475526 | BRAF | B-Raf proto-oncogene, serine/threonine kinase | 9615 | VGNC:38514 | Inparanoid, OMA, EggNOG |
| Horse | 100065760 | BRAF | B-Raf proto-oncogene, serine/threonine kinase | 9796 | VGNC:15875 | Inparanoid, OMA, EggNOG |
| Cow | 536051 | BRAF | B-Raf proto-oncogene, serine/threonine kinase | 9913 | VGNC:26551 | OMA, EggNOG |
| Pig | 100514612 | BRAF | B-Raf proto-oncogene, serine/threonine kinase | 9823 | OMA, EggNOG | |
| Opossum | 100024057 | BRAF | B-Raf proto-oncogene, serine/threonine kinase | 13616 | Inparanoid, OMA, EggNOG | |
| Chicken | 396239 | BRAF | B-Raf proto-oncogene, serine/threonine kinase | 9031 | CGNC:9744 | Inparanoid, OMA |
| Anole lizard | 100556317 | braf | B-Raf proto-oncogene, serine/threonine kinase | 28377 | Inparanoid, OMA | |
| Xenopus | 779570 | braf | B-Raf proto-oncogene, serine/threonine kinase | 8364 | XB-GENE-1014202 | Inparanoid, OMA |
| Zebrafish | 403065 | braf | B-Raf proto-oncogene, serine/threonine kinase | 7955 | ZDB-GENE-040805-1 | Inparanoid, OMA |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / TKL group / RAF family / Serine/threonine-protein kinase b-raf
protein / Kinase / Protein kinase / TKL group / RAF family / Serine/threonine-protein kinase b-raf
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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