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BUB1

DescriptionMitotic checkpoint serine/threonine-protein kinase BUB1

Gene and Protein Information

Gene ID699
Uniprot Accession IDs O43683 E9PC26 F5GXI5 O43430 O43643 O60626 Q53QE4 hBUB1
Ensembl ID ENSP00000302530
Symbol BUB1L BUB1A BUB1L hBUB1
FamilyBelongs to the protein kinase superfamily. Ser/Thr protein kinase family. BUB1 subfamily.
Sequence
MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKKKYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASAVLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGNNMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKEKLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKLHQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPPVVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSGAEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTLPDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGLPQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDFTSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEKSPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQAEWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEFQLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFRRLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLECKRSRK
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp459484BUB1BUB1 mitotic checkpoint serine/threonine kinase9598VGNC:177OMA, EggNOG
Macaque696598BUB1BUB1 mitotic checkpoint serine/threonine kinase9544Inparanoid, OMA, EggNOG
Mouse12235Bub1BUB1, mitotic checkpoint serine/threonine kinase10090MGI:1100510Inparanoid, OMA, EggNOG
Rat296137Bub1BUB1 mitotic checkpoint serine/threonine kinase10116RGD:1311707Inparanoid, OMA, EggNOG
Dog100682599BUB1BUB1 mitotic checkpoint serine/threonine kinase9615VGNC:38565Inparanoid, OMA, EggNOG
Horse100064049BUB1BUB1 mitotic checkpoint serine/threonine kinase9796VGNC:15924Inparanoid, OMA, EggNOG
Cow514777BUB1BUB1 mitotic checkpoint serine/threonine kinase9913VGNC:26604Inparanoid, OMA, EggNOG
Opossum100033212BUB1BUB1 mitotic checkpoint serine/threonine kinase13616Inparanoid, EggNOG
Platypus100073976BUB1BUB1 mitotic checkpoint serine/threonine kinase9258Inparanoid, OMA, EggNOG
Chicken421226BUB1BUB1 mitotic checkpoint serine/threonine kinase9031CGNC:6238Inparanoid, OMA, EggNOG
Anole lizard100559298bub1BUB1 mitotic checkpoint serine/threonine kinase28377Inparanoid, OMA, EggNOG
Xenopus780291bub1BUB1 mitotic checkpoint serine/threonine kinase8364XB-GENE-974762Inparanoid, OMA, EggNOG
Zebrafish100307076bub1BUB1 mitotic checkpoint serine/threonine kinase7955ZDB-GENE-081104-75OMA, EggNOG
Fruitfly35522BubR1Bub1-related kinase7227FBgn0263855Inparanoid, EggNOG
S.cerevisiae853100BUB1protein kinase BUB14932S000003420Inparanoid, EggNOG

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    Other group    /    BUB family    /    Mitotic checkpoint serine/threonine-protein kinase bub1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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