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CACNA1S

DescriptionVoltage-dependent L-type calcium channel subunit alpha-1S

Gene and Protein Information

Gene ID779
Uniprot Accession IDs Q13698 A4IF51 B1ALM2 Q12896 Q13934
Ensembl ID ENSP00000355192
Symbol CACH1 CACN1 CACNL1A3 MHS5 HOKPP TTPP1 Cav1.1 HOKPP1 hypoPP CCHL1A3 CACNL1A3
FamilyBelongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1S subfamily.
Sequence
MEPSSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLENPLRKACISIVEWKPFETIILLTIFANCVALAVYLPMPEDDNNSLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFTIVFLGVFTVILEQVNVIQSHTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEEPSPCARTGSGRRCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLDEDLRGYMSWITQGEVMDVEDFREGKLSLDEGGSDTESLYEIAGLNKIIQFIRHWRQWNRIFRWKCHDIVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTRLQDIANRVLLSLFTTEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRIFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWTSMMYNGIMAYGGPSYPGMLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKAKAEEKKRRKMSKGLPDKSEEEKSTMAKKLEQKPKGEGIPTTAKLKIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPLSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILKHFDIGFTSVFTVEIVLKMTTYGAFLHKGSFCRNYFNMLDLLVVAVSLISMGLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCMFVAISTIGNIVLVTTLLQFMFACIGVQLFKGKFFRCTDLSKMTEEECRGYYYVYKDGDPMQIELRHREWVHSDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNAEDVGPIYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYIVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDILNVAFTIIFTLEMILKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILSEIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPESDYAPGEEYTCGTNFAYYYFISFYMLCAFLVINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKRTSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDIVQIQAGLRTIEEEAAPEICRTVSGDLAAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLPPVMANQRPLQFAEIEMEEMESPVFLEDFPQDPRTNPLARANTNNANANVAYGNSNHSNSHVFSSVHYEREFPEETETPATRGRALGQPCRVLGPHSKPCVEMLKGLLTQRAMPRGQAPPAPCQCPRVESSMPEDRKSSTPGSLHEETPHSRSTRENTSRCSAPATALLIQKALVRGGLGTLAADANFIMATGQALADACQMEPEEVEIMATELLKGREAPEGMASSLGCLNLGSSLGSLDQHQGSQETLIPPRL
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp469635CACNA1Scalcium voltage-gated channel subunit alpha1 S9598VGNC:11750Inparanoid, OMA, EggNOG
Mouse12292Cacna1scalcium channel, voltage-dependent, L type, alpha 1S subunit10090MGI:88294Inparanoid, OMA, EggNOG
Rat682930Cacna1scalcium voltage-gated channel subunit alpha1 S10116RGD:70983OMA, EggNOG
Dog490244CACNA1Scalcium voltage-gated channel subunit alpha1 S9615VGNC:38640Inparanoid, OMA, EggNOG
Horse100034092CACNA1Scalcium voltage-gated channel subunit alpha1 S9796VGNC:15987Inparanoid, OMA, EggNOG
CowCACNA1Scalcium voltage-gated channel subunit alpha1 S [Source:HGNC Symbol;Acc:HGNC:1397]9913OMA, EggNOG
Pig100622149CACNA1Scalcium voltage-gated channel subunit alpha1 S9823OMA, EggNOG
Opossum100013684CACNA1Scalcium voltage-gated channel subunit alpha1 S13616Inparanoid, OMA, EggNOG
Anole lizard100551605cacna1scalcium voltage-gated channel subunit alpha1 S28377Inparanoid, OMA
Zebrafish405791cacna1sbcalcium channel, voltage-dependent, L type, alpha 1S subunit, b7955ZDB-GENE-051227-1Inparanoid, OMA
C. elegans177513egl-19Uncharacterized protein6239Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Ion channel    /    Calcium channel alpha-1 subunit family    /    CACNA1S subfamily    /    Voltage-dependent l-type calcium channel subunit alpha-1s

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

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