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| Description | Serine/threonine-protein kinase A-Raf |
|---|
Gene and Protein Information
| Gene ID | 369 |
|---|---|
| Uniprot Accession IDs | P10398 P07557 Q5H9B2 Q5H9B3 |
| Ensembl ID | ENSP00000290277 |
| Symbol | ARAF1 PKS PKS2 PKS2 A-RAF ARAF1 RAFA1 |
| Family | Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. |
| Sequence | MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCVVYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQDLSGGSRQHEAPSNRPLNELLTPQGPSPRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLTGQSFSTDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPACLLSAARLVP Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 100614256 | ARAF | A-Raf proto-oncogene, serine/threonine kinase | 9598 | Inparanoid, OMA | |
| Macaque | 707169 | ARAF | A-Raf proto-oncogene, serine/threonine kinase | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 11836 | Araf | Araf proto-oncogene, serine/threonine kinase | 10090 | MGI:88065 | Inparanoid, OMA, EggNOG |
| Rat | 64363 | Araf | A-Raf proto-oncogene, serine/threonine kinase | 10116 | RGD:2148 | Inparanoid, OMA |
| Dog | 491857 | ARAF | A-Raf proto-oncogene, serine/threonine kinase | 9615 | VGNC:38024 | Inparanoid, OMA |
| Horse | 100061212 | ARAF | A-Raf proto-oncogene, serine/threonine kinase | 9796 | VGNC:15438 | Inparanoid, OMA |
| Cow | 540421 | ARAF | A-Raf proto-oncogene, serine/threonine kinase | 9913 | VGNC:26054 | Inparanoid, OMA |
| Pig | 397601 | ARAF | A-Raf proto-oncogene, serine/threonine kinase | 9823 | Inparanoid, OMA | |
| Platypus | 100084423 | ARAF | A-Raf proto-oncogene, serine/threonine kinase | 9258 | Inparanoid, OMA | |
| Anole lizard | 100562070 | araf | A-Raf proto-oncogene, serine/threonine kinase | 28377 | Inparanoid, OMA | |
| Zebrafish | 403063 | araf | A-Raf proto-oncogene, serine/threonine kinase | 7955 | ZDB-GENE-050102-2 | Inparanoid, OMA |
| Fruitfly | 31221 | Raf | Raf oncogene | 7227 | FBgn0003079 | Inparanoid, OMA |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / TKL group / RAF family / Serine/threonine-protein kinase a-raf
protein / Kinase / Protein kinase / TKL group / RAF family / Serine/threonine-protein kinase a-raf
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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