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ATP4A

DescriptionPotassium-transporting ATPase alpha chain 1

Gene and Protein Information

Gene ID495
Uniprot Accession IDs P20648 O00738
Ensembl ID ENSP00000262623
Symbol ATP6A
FamilyBelongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
Sequence
MGKAENYELYSVELGPGPGGDMAAKMSKKKKAGGGGGKRKEKLENMKKEMEINDHQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQWEDHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRKLGVRCCPGSWWDQELYY
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp747915ATP4AATPase H+/K+ transporting subunit alpha9598VGNC:7612OMA, EggNOG
MacaqueATP4AATPase H+/K+ transporting alpha subunit [Source:HGNC Symbol;Acc:HGNC:819]9544OMA, EggNOG
Mouse11944Atp4aATPase, H+/K+ exchanging, gastric, alpha polypeptide10090MGI:88113Inparanoid, OMA, EggNOG
Rat24216Atp4aATPase H+/K+ transporting subunit alpha10116RGD:2177Inparanoid, OMA, EggNOG
Dog431686ATP4AATPase H+/K+ transporting subunit alpha9615VGNC:38262Inparanoid, OMA, EggNOG
Horse100147108ATP4AATPase H+/K+ transporting subunit alpha9796VGNC:50998Inparanoid, OMA, EggNOG
Cow521163ATP4AATPase H+/K+ transporting alpha subunit9913Inparanoid, OMA, EggNOG
Pig397552ATP4AATPase H+/K+ transporting alpha subunit9823Inparanoid, OMA, EggNOG
Opossum100013166ATP4AATPase H+/K+ transporting alpha subunit13616Inparanoid, OMA, EggNOG
Anole lizard100563553atp4aATPase H+/K+ transporting alpha subunit28377Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    transporter    /    ion channel    /    Potassium-transporting ATPase alpha chain 1
protein    /    transporter    /    cation transporter    /    Potassium-transporting ATPase alpha chain 1
protein    /    transporter    /    hydrolase    /    Potassium-transporting ATPase alpha chain 1
DTO Classes
protein    /    Transporter    /    P-type ATPases    /    H+/K+-ATPases    /    Potassium-transporting ATPase alpha chain 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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