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| Description | Cyclin-dependent kinase 12 |
|---|
Gene and Protein Information
| Gene ID | 51755 |
|---|---|
| Uniprot Accession IDs | Q9NYV4 A7E2B2 B4DYX4 B9EIQ6 O94978 |
| Ensembl ID | ENSP00000398880 |
| Symbol | CRK7 CRKRS KIAA0904 CRK7 CRKR CRKRS |
| Family | Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. |
| Sequence | MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEAASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQANSQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQRTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHILPPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNYGELGPGTTGASSSGAGLHWGGPTQSSAYGKLYRGPTRVPPRGGRGRGVPY Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 454630 | CDK12 | cyclin dependent kinase 12 | 9598 | VGNC:9182 | OMA, EggNOG |
| Macaque | 696733 | CDK12 | cyclin dependent kinase 12 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 69131 | Cdk12 | cyclin-dependent kinase 12 | 10090 | MGI:1098802 | Inparanoid, OMA, EggNOG |
| Rat | 192350 | Cdk12 | cyclin-dependent kinase 12 | 10116 | RGD:621111 | Inparanoid, OMA, EggNOG |
| Dog | 491027 | CDK12 | cyclin dependent kinase 12 | 9615 | VGNC:39044 | Inparanoid, OMA, EggNOG |
| Horse | 100068316 | CDK12 | cyclin dependent kinase 12 | 9796 | VGNC:16341 | Inparanoid, OMA, EggNOG |
| Cow | 511513 | CDK12 | cyclin dependent kinase 12 | 9913 | VGNC:27117 | Inparanoid, OMA |
| Pig | 100513815 | CDK12 | cyclin dependent kinase 12 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100017594 | CDK12 | cyclin dependent kinase 12 | 13616 | OMA, EggNOG | |
| Chicken | 428306 | CDK12 | cyclin dependent kinase 12 | 9031 | CGNC:53328 | Inparanoid, OMA, EggNOG |
| Xenopus | 100038049 | cdk12 | cyclin-dependent kinase 12 | 8364 | XB-GENE-493308 | Inparanoid, OMA, EggNOG |
| Zebrafish | 100149834 | cdk12 | cyclin-dependent kinase 12 | 7955 | ZDB-GENE-081104-294 | Inparanoid, OMA |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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