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| Description | Tyrosine-protein kinase ZAP-70 |
|---|
Gene and Protein Information
| Gene ID | 7535 |
|---|---|
| Uniprot Accession IDs | P43403 A6NFP4 Q6PIA4 Q8IXD6 Q9UBS6 |
| Ensembl ID | ENSP00000264972 |
| Symbol | SRK SRK STD TZK STCD IMD48 ADMIO2 ZAP-70 |
| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily. |
| Sequence | MPDPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGTYAIAGGKAHCGPAELCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTAHERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLVEYLKLKADGLIYCLKEACPNSSASNASGAAAPTLPAHPSTLTHPQRRIDTLNSDGYTPEPARITSPDKPRPMPMDTSVYESPYSDPEELKDKKLFLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYIVRLIGVCQAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYKWEDRPDFLTVEQRMRACYYSLASKVEGPPGSTQKAEAACA Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 459427 | ZAP70 | zeta chain of T cell receptor associated protein kinase 70 | 9598 | VGNC:2916 | OMA, EggNOG |
| Macaque | 707555 | LOC707555 | tyrosine-protein kinase ZAP-70 | 9544 | OMA, EggNOG | |
| Mouse | 22637 | Zap70 | zeta-chain (TCR) associated protein kinase | 10090 | MGI:99613 | Inparanoid, OMA, EggNOG |
| Rat | 301348 | Zap70 | zeta chain of T cell receptor associated protein kinase 70 | 10116 | RGD:3983 | Inparanoid, EggNOG |
| Dog | 100271860 | ZAP70 | zeta chain of T cell receptor associated protein kinase 70 | 9615 | VGNC:54555 | Inparanoid, OMA |
| Horse | 100147296 | ZAP70 | zeta chain of T-cell receptor associated protein kinase 70 | 9796 | VGNC:25124 | Inparanoid, OMA |
| Cow | 504509 | ZAP70 | zeta chain of T-cell receptor associated protein kinase 70 | 9913 | VGNC:37050 | Inparanoid, OMA |
| Pig | 100739325 | LOC100739325 | tyrosine-protein kinase ZAP-70 | 9823 | Inparanoid, OMA | |
| Chicken | 420086 | ZAP70 | zeta-chain (TCR) associated protein kinase 70kDa | 9031 | CGNC:1027 | Inparanoid, OMA |
| Xenopus | 448557 | zap70 | zeta chain of T cell receptor associated protein kinase 70 | 8364 | XB-GENE-956409 | Inparanoid, OMA |
| Zebrafish | 553615 | zap70 | zeta chain of T cell receptor associated protein kinase 70 | 7955 | ZDB-GENE-050522-257 | Inparanoid, OMA |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / TK group / SYK family / Tyrosine-protein kinase zap-70
protein / Kinase / Protein kinase / TK group / SYK family / Tyrosine-protein kinase zap-70
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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