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| Description | Cytoplasmic aconitate hydratase |
|---|
Gene and Protein Information
| Gene ID | 48 |
|---|---|
| Uniprot Accession IDs | P21399 D3DRK7 Q14652 Q5VZA7 Aconitase |
| Ensembl ID | ENSP00000309477 |
| Symbol | IREB1 IRP1 ACONS HEL60 IREB1 IREBP IREBP1 |
| Family | Belongs to the aconitase/IPM isomerase family. |
| Sequence | MSNPFAHLAEPLDPVQPGKKFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDIENILHWNVTQHKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCPADLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQVNLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVLPQVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMCPEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVVELDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAKQGFKGFQVAPEHHNDHKTFIYDNTEFTLAHGSVVIAAITSCTNTSNPSVMLGAGLLAKKAVDAGLNVMPYIKTSLSPGSGVVTYYLQESGVMPYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDLVAVGVLSGNRNFEGRVHPNTRANYLASPPLVIAYAIAGTIRIDFEKEPLGVNAKGQQVFLKDIWPTRDEIQAVERQYVIPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTLDLQPPKSIVDAYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAVMARGTFANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAGKEYGAGSSRDWAAKGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTGQERYTIIIPENLKPQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMIRKMAK Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 465034 | ACO1 | aconitase 1 | 9598 | VGNC:8797 | OMA, EggNOG |
| Macaque | 705075 | ACO1 | aconitase 1 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 11428 | Aco1 | aconitase 1 | 10090 | MGI:87879 | Inparanoid, OMA, EggNOG |
| Rat | 50655 | Aco1 | aconitase 1 | 10116 | RGD:2019 | Inparanoid, OMA, EggNOG |
| Dog | 481576 | ACO1 | aconitase 1 | 9615 | VGNC:37513 | Inparanoid, OMA, EggNOG |
| Horse | 100067866 | ACO1 | aconitase 1 | 9796 | VGNC:14985 | Inparanoid, OMA, EggNOG |
| Cow | 512995 | ACO1 | aconitase 1 | 9913 | VGNC:25545 | Inparanoid, OMA, EggNOG |
| Pig | 100628006 | ACO1 | aconitase 1 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100016997 | ACO1 | aconitase 1 | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | 100076717 | ACO1 | aconitase 1 | 9258 | Inparanoid, OMA, EggNOG | |
| Chicken | 373916 | ACO1 | aconitase 1, soluble | 9031 | CGNC:48955 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100555878 | aco1 | aconitase 1 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100216202 | aco1 | aconitase 1 | 8364 | XB-GENE-1012108 | Inparanoid, OMA |
| Zebrafish | 568448 | aco1 | aconitase 1, soluble | 7955 | ZDB-GENE-031118-76 | Inparanoid, OMA |
| C. elegans | 181324 | aco-1 | Probable cytoplasmic aconitate hydratase | 6239 | Inparanoid, OMA, EggNOG | |
| Fruitfly | 42689 | Irp-1A | Iron regulatory protein 1A | 7227 | FBgn0024958 | Inparanoid, EggNOG |
Protein Classes
PANTHER Classes
protein / lyase / dehydratase / Cytoplasmic aconitate hydratase
protein / lyase / hydratase / Cytoplasmic aconitate hydratase
protein / lyase / dehydratase / Cytoplasmic aconitate hydratase
protein / lyase / hydratase / Cytoplasmic aconitate hydratase
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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