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CHRNA4

DescriptionNeuronal acetylcholine receptor subunit alpha-4

Gene and Protein Information

Gene ID1137
Uniprot Accession IDs P43681 Q4JGR7 Q4VAQ5 Q4VAQ6
Ensembl ID ENSP00000359285
Symbol NACRA4 EBN BFNC EBN1 NACHR NACRA4 NACHRA4
FamilyBelongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-4/CHRNA4 sub-subfamily.
Sequence
MELGGPGAPRLLPPLLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVDAVGTYNTRKYECCAEIYPDITYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPRTHTMPTWVRRVFLDIVPRLLLMKRPSVVKDNCRRLIESMHKMASAPRFWPEPEGEPPATSGTQSLHPPSPSFCVPLDVPAEPGPSCKSPSDQLPPQQPLEAEKASPHPSPGPCRPPHGTQAPGLAKARSLSVQHMSSPGEAVEGGVRCRSRSIQYCVPRDDAAPEADGQAAGALASRNTHSAELPPPDQPSPCKCTCKKEPSSVSPSATVKTRSTKAPPPHLPLSPALTRAVEGVQYIADHLKAEDTDFSVKEDWKYVAMVIDRIFLWMFIIVCLLGTVGLFLPPWLAGMI
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp469999CHRNA4cholinergic receptor nicotinic alpha 4 subunit9598VGNC:51755Inparanoid, OMA, EggNOG
MacaqueCHRNA4cholinergic receptor nicotinic alpha 4 subunit [Source:HGNC Symbol;Acc:HGNC:1958]9544Inparanoid, OMA, EggNOG
Mouse11438Chrna4cholinergic receptor, nicotinic, alpha polypeptide 410090MGI:87888Inparanoid, OMA, EggNOG
Rat25590Chrna4cholinergic receptor nicotinic alpha 4 subunit10116RGD:2346Inparanoid, OMA, EggNOG
Dog485972CHRNA4cholinergic receptor nicotinic alpha 4 subunit9615VGNC:39239Inparanoid, OMA
Cow537251CHRNA4cholinergic receptor nicotinic alpha 4 subunit9913VGNC:27326Inparanoid, OMA
Platypus100075024CHRNA4cholinergic receptor nicotinic alpha 4 subunit9258Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    transporter    /    ligand-gated ion channel    /    Neuronal acetylcholine receptor subunit alpha-4
protein    /    transporter    /    ion channel    /    Neuronal acetylcholine receptor subunit alpha-4
protein    /    transporter    /    acetylcholine receptor    /    Neuronal acetylcholine receptor subunit alpha-4
protein    /    transporter    /    GABA receptor    /    Neuronal acetylcholine receptor subunit alpha-4
protein    /    transporter    /    receptor    /    Neuronal acetylcholine receptor subunit alpha-4
DTO Classes
protein    /    Ion channel    /    Neurotransmitter receptor, Cys loop, ligand-gated ion channel (LIC) family    /    Acetylcholine receptor subfamily    /    Alpha-4/CHRNA4 sub-subfamily    /    Neuronal acetylcholine receptor subunit alpha-4

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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