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| Description | Cytosolic 10-formyltetrahydrofolate dehydrogenase |
|---|
Gene and Protein Information
| Gene ID | 10840 |
|---|---|
| Uniprot Accession IDs | O75891 B4DG36 E9PBX3 Q68CS1 Q8TBP8 10-FTHFDH |
| Ensembl ID | ENSP00000273450 |
| Symbol | FTHFD FDH FTHFD 10-fTHF 10-FTHFDH |
| Family | In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. |
| Sequence | MKIAVIGQSLFGQEVYCHLRKEGHEVVGVFTVPDKDGKADPLGLEAEKDGVPVFKYSRWRAKGQALPDVVAKYQALGAELNVLPFCSQFIPMEIISAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFSIFWADDGLDTGDLLLQKECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGKAPRLPQPEEGATYEGIQKKETAKINWDQPAEAIHNWIRGNDKVPGAWTEACEQKLTFFNSTLNTSGLVPEGDALPIPGAHRPGVVTKAGLILFGNDDKMLLVKNIQLEDGKMILASNFFKGAASSVLELTEAELVTAEAVRSVWQRILPKVLEVEDSTDFFKSGAASVDVVRLVEEVKELCDGLELENEDVYMASTFGDFIQLLVRKLRGDDEEGECSIDYVEMAVNKRTVRMPHQLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFENGRWGKISARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDEFVRRVVEEVRKMKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPRPGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRVKTVTFEY Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Macaque | 716977 | ALDH1L1 | aldehyde dehydrogenase 1 family member L1 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 107747 | Aldh1l1 | aldehyde dehydrogenase 1 family, member L1 | 10090 | MGI:1340024 | Inparanoid, OMA, EggNOG |
| Rat | 64392 | Aldh1l1 | aldehyde dehydrogenase 1 family, member L1 | 10116 | RGD:621294 | Inparanoid, OMA |
| Horse | 100061108 | ALDH1L1 | aldehyde dehydrogenase 1 family member L1 | 9796 | VGNC:15232 | Inparanoid, OMA |
| Cow | 505677 | ALDH1L1 | aldehyde dehydrogenase 1 family member L1 | 9913 | VGNC:25811 | Inparanoid, OMA |
| Opossum | 100026594 | ALDH1L1 | aldehyde dehydrogenase 1 family member L1 | 13616 | Inparanoid, OMA | |
| Xenopus | 496436 | aldh1l1 | aldehyde dehydrogenase 1 family member L1 | 8364 | XB-GENE-1016237 | Inparanoid, OMA |
| C. elegans | 177999 | alh-3 | 10-formyltetrahydrofolate dehydrogenase | 6239 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / oxidoreductase / dehydrogenase / Cytosolic 10-formyltetrahydrofolate dehydrogenase
protein / oxidoreductase / dehydrogenase / Cytosolic 10-formyltetrahydrofolate dehydrogenase
DTO Classes
protein / Enzyme / Oxidoreductase / Dehydrogenase / Cytosolic 10-formyltetrahydrofolate dehydrogenase
protein / Enzyme / Oxidoreductase / Dehydrogenase / Cytosolic 10-formyltetrahydrofolate dehydrogenase
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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