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ABCC8

DescriptionATP-binding cassette sub-family C member 8

Gene and Protein Information

Gene ID6833
Uniprot Accession IDs Q09428 A6NMX8 E3UYX6 O75948 Q16583
Ensembl ID ENSP00000303960
Symbol HRINS SUR SUR1 HI SUR HHF1 MRP8 PHHI SUR1 ABC36 HRINS TNDM2 SUR1delta2
FamilyBelongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Sequence
MPLAFCGSENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHIHHSTWLHFPGHNLRWILTFMLLFVLVCEIAEGILSDGVTESHHLHLYMPAGMAFMAAVTSVVYYHNIETSNFPKLLIALLVYWTLAFITKTIKFVKFLDHAIGFSQLRFCLTGLLVILYGMLLLVEVNVIRVRRYIFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHKKPIDLRAIGKLPIAMRALTNYQRLCEAFDAQVRKDIQGTQGARAIWQALSHAFGRRLVLSSTFRILADLLGFAGPLCIFGIVDHLGKENDVFQPKTQFLGVYFVSSQEFLANAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFRTRVETTRRKEMTSLRAFAIYTSISIFMNTAIPIAAVLITFVGHVSFFKEADFSPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQCAPHEPTPQGPASKYQAVPLRVVNRKRPAREDCRGLTGPLQSLVPSADGDADNCCVQIMGGYFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLAALGEMQKVSGAVFWSSLPDSEIGEDPSPERETATDLDIRKRGPVAYASQKPWLLNATVEENIIFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVTERKATEPPQGLSRAMSSRDGLLQDEEEEEEEAAESEEDDNLSSMLHQRAEIPWRACAKYLSSAGILLLSLLVFSQLLKHMVLVAIDYWLAKWTDSALTLTPAARNCSLSQECTLDQTVYAMVFTVLCSLGIVLCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALAVISYVTPVFLVALLPLAIVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVLIAAVTSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMELQLGAVKRIHGLLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNALIAPGQKIGICGRTGSGKSSFSLAFFRMVDTFEGHIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPERKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVIVLKRGAILEFDKPEKLLSRKDSVFASFVRADK
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp451056ABCC8ATP binding cassette subfamily C member 89598VGNC:11253OMA, EggNOG
Macaque654490ABCC8ATP binding cassette subfamily C member 89544Inparanoid, OMA
Mouse20927Abcc8ATP-binding cassette, sub-family C (CFTR/MRP), member 810090MGI:1352629Inparanoid, OMA, EggNOG
Rat25559Abcc8ATP binding cassette subfamily C member 810116RGD:3786Inparanoid, OMA, EggNOG
Dog485402ABCC8ATP binding cassette subfamily C member 89615VGNC:37443Inparanoid, OMA
Horse100071788ABCC8ATP binding cassette subfamily C member 89796VGNC:14921Inparanoid, OMA
Cow538996ABCC8ATP binding cassette subfamily C member 89913VGNC:25475Inparanoid, OMA, EggNOG
Pig100158245ABCC8ATP binding cassette subfamily C member 89823Inparanoid, OMA, EggNOG
Opossum100020181ABCC8ATP binding cassette subfamily C member 813616Inparanoid, OMA
PlatypusABCC8ATP binding cassette subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:59]9258OMA, EggNOG
Chicken423072ABCC8ATP binding cassette subfamily C member 89031CGNC:4631Inparanoid, OMA, EggNOG
Anole lizard100562467abcc8ATP binding cassette subfamily C member 828377Inparanoid, OMA
Zebrafish553281abcc8ATP-binding cassette, sub-family C (CFTR/MRP), member 87955ZDB-GENE-050517-22Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    transporter    /    ATP-binding cassette (ABC) transporter    /    ATP-binding cassette sub-family C member 8
DTO Classes
protein    /    Transporter    /    ATP-binding cassette transporter family    /    ABCC subfamily    /    ATP-binding cassette sub-family C member 8

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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