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| Description | Histone-lysine N-methyltransferase EZH2 |
|---|
Gene and Protein Information
| Gene ID | 2146 |
|---|---|
| Uniprot Accession IDs | Q15910 B2RAQ1 B3KS30 B7Z1D6 B7Z7L6 Q15755 Q75MG3 Q92857 Q96FI6 |
| Ensembl ID | ENSP00000320147 |
| Symbol | KMT6 WVS ENX1 KMT6 WVS2 ENX-1 EZH2b KMT6A |
| Family | Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. EZ subfamily. |
| Sequence | MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFPDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRRGRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 745437 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 9598 | VGNC:4343 | OMA, EggNOG |
| Macaque | 709075 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 14056 | Ezh2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 10090 | MGI:107940 | Inparanoid, OMA, EggNOG |
| Rat | 312299 | Ezh2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 10116 | RGD:1595860 | Inparanoid, OMA, EggNOG |
| Dog | 475511 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 9615 | VGNC:40541 | Inparanoid, OMA, EggNOG |
| Horse | 100051290 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 9796 | VGNC:17750 | Inparanoid, OMA, EggNOG |
| Cow | 509106 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 9913 | VGNC:28675 | Inparanoid, OMA, EggNOG |
| Pig | 100625497 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100013390 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 13616 | OMA, EggNOG | |
| Platypus | 100073485 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 9258 | Inparanoid, OMA, EggNOG | |
| Anole lizard | 100564989 | ezh2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 28377 | Inparanoid, OMA | |
| Xenopus | ezh2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:Xenbase;Acc:XB-GENE-956215] | 8364 | OMA, EggNOG | ||
| Zebrafish | 768133 | ezh2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 7955 | ZDB-GENE-041111-259 | Inparanoid, OMA, EggNOG |
Protein Classes
DTO Classes
protein / Epigenetic regulator / Writer / Protein methyltransferase / Histone-lysine N-methyltransferase EZH2
protein / Epigenetic regulator / Writer / Protein methyltransferase / Histone-lysine N-methyltransferase EZH2
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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