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| Description | Serine/threonine-protein kinase Chk1 |
|---|
Gene and Protein Information
| Gene ID | 1111 |
|---|---|
| Uniprot Accession IDs | O14757 A8K934 B4DDD0 B4DSK3 B5BTY6 F5H7S4 H2BI51 |
| Ensembl ID | ENSP00000388648 |
| Symbol | CHK1 CHK1 |
| Family | Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily. |
| Sequence | MAVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDFSPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLLGTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRRNNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 739836 | CHEK1 | checkpoint kinase 1 | 9598 | VGNC:11294 | OMA, EggNOG |
| Mouse | 12649 | Chek1 | checkpoint kinase 1 | 10090 | MGI:1202065 | Inparanoid, OMA, EggNOG |
| Rat | Chek1 | checkpoint kinase 1 [Source:RGD Symbol;Acc:620545] | 10116 | Inparanoid, EggNOG | ||
| Dog | 609767 | CHEK1 | checkpoint kinase 1 | 9615 | VGNC:53319 | Inparanoid, OMA, EggNOG |
| Horse | 100064353 | CHEK1 | checkpoint kinase 1 | 9796 | VGNC:49356 | Inparanoid, OMA, EggNOG |
| Cow | 513678 | CHEK1 | checkpoint kinase 1 | 9913 | VGNC:50058 | Inparanoid, OMA, EggNOG |
| Pig | 100511709 | CHEK1 | checkpoint kinase 1 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100016170 | CHEK1 | checkpoint kinase 1 | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | 100090345 | CHEK1 | checkpoint kinase 1 | 9258 | Inparanoid, OMA, EggNOG | |
| Anole lizard | 100564808 | chek1 | checkpoint kinase 1 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100038224 | chek1 | checkpoint kinase 1 | 8364 | XB-GENE-491846 | Inparanoid, OMA, EggNOG |
| Zebrafish | 393162 | chek1 | checkpoint kinase 1 | 7955 | ZDB-GENE-040426-896 | Inparanoid, OMA |
| C. elegans | 3565921 | chk-1 | Serine/threonine-protein kinase chk-1 | 6239 | Inparanoid, OMA | |
| S.cerevisiae | 852577 | CHK1 | serine/threonine protein kinase CHK1 | 4932 | S000000478 | Inparanoid, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
|---|
Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
|---|
Bibliography
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