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CHEK2

DescriptionSerine/threonine-protein kinase Chk2

Gene and Protein Information

Gene ID11200
Uniprot Accession IDs O96017 A8K3Y9 B7ZBF3 B7ZBF4 B7ZBF5 Q6QA03 Q6QA04 Q6QA05 Q6QA06 Q6QA07 Q6QA08 Q6QA10 Q6QA11 Q6QA12 Q6QA13 Q9HBS5 Q9HCQ8 Q9UGF0 Q9UGF1
Ensembl ID ENSP00000372023
Symbol CDS1 CHK2 RAD53 CDS1 CHK2 LFS2 RAD53 hCds1 HuCds1 PP1425
FamilyBelongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHK2 subfamily.
Sequence
MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp458733CHEK2checkpoint kinase 29598VGNC:12828OMA, EggNOG
Macaque713668CHEK2checkpoint kinase 29544Inparanoid, OMA, EggNOG
Mouse50883Chek2checkpoint kinase 210090MGI:1355321Inparanoid, OMA, EggNOG
Rat114212Chek2checkpoint kinase 210116RGD:621543Inparanoid, OMA, EggNOG
Dog486338CHEK2checkpoint kinase 29615VGNC:39209Inparanoid, OMA, EggNOG
Horse100059288CHEK2checkpoint kinase 29796VGNC:16493Inparanoid, OMA, EggNOG
Cow518897CHEK2checkpoint kinase 29913VGNC:27286Inparanoid, OMA, EggNOG
Opossum100030584CHEK2checkpoint kinase 213616Inparanoid, OMA, EggNOG
Platypus100077482CHEK2checkpoint kinase 29258Inparanoid, OMA, EggNOG
Chicken768913CHEK2checkpoint kinase 29031CGNC:4245Inparanoid, OMA, EggNOG
Xenopus100144952chek2checkpoint kinase 28364XB-GENE-5765421Inparanoid, OMA, EggNOG
Zebrafish336998chek2checkpoint kinase 27955ZDB-GENE-030131-8942Inparanoid, OMA, EggNOG
Fruitfly35288lokloki7227FBgn0019686Inparanoid, EggNOG

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    CAMK group    /    RAD53 family    /    Serine/threonine-protein kinase chk2

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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