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| Description | Epidermal growth factor receptor |
|---|
Gene and Protein Information
| Gene ID | 1956 |
|---|---|
| Uniprot Accession IDs | P00533 O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5 |
| Ensembl ID | ENSP00000275493 |
| Symbol | ERBB ERBB1 HER1 ERBB HER1 mENA ERBB1 PIG61 NISBD2 |
| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily. |
| Sequence | MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 463415 | EGFR | epidermal growth factor receptor | 9598 | VGNC:4334 | OMA, EggNOG |
| Macaque | 613027 | EGFR | epidermal growth factor receptor | 9544 | OMA, EggNOG | |
| Mouse | 13649 | Egfr | epidermal growth factor receptor | 10090 | MGI:95294 | Inparanoid, OMA, EggNOG |
| Rat | 24329 | Egfr | epidermal growth factor receptor | 10116 | RGD:2543 | Inparanoid, OMA, EggNOG |
| Dog | 404306 | EGFR | epidermal growth factor receptor | 9615 | VGNC:51866 | Inparanoid, OMA, EggNOG |
| Horse | 100067755 | EGFR | epidermal growth factor receptor | 9796 | VGNC:17460 | Inparanoid, OMA, EggNOG |
| Cow | 407217 | EGFR | epidermal growth factor receptor | 9913 | VGNC:28366 | Inparanoid, OMA, EggNOG |
| Pig | 397070 | EGFR | epidermal growth factor receptor | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100029625 | EGFR | epidermal growth factor receptor | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | 100075894 | EGFR | epidermal growth factor receptor | 9258 | Inparanoid, OMA, EggNOG | |
| Anole lizard | 100562231 | egfr | epidermal growth factor receptor | 28377 | Inparanoid, OMA | |
| Xenopus | 100492965 | egfr | epidermal growth factor receptor | 8364 | XB-GENE-6067152 | Inparanoid, OMA |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / TK group / EGFR family / Epidermal growth factor receptor
protein / Kinase / Protein kinase / TK group / EGFR family / Epidermal growth factor receptor
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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