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| Description | Tyrosine-protein kinase receptor Tie-1 |
|---|
Gene and Protein Information
| Gene ID | 7075 |
|---|---|
| Uniprot Accession IDs | P35590 B5A949 B5A950 |
| Ensembl ID | ENSP00000361554 |
| Symbol | TIE TIE JTK14 |
| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. Tie subfamily. |
| Sequence | MVWRVPPFLLPILFLASHVGAAVDLTLLANLRLTDPQRFFLTCVSGEAGAGRGSDAWGPPLLLEKDDRIVRTPPGPPLRLARNGSHQVTLRGFSKPSDLVGVFSCVGGAGARRTRVIYVHNSPGAHLLPDKVTHTVNKGDTAVLSARVHKEKQTDVIWKSNGSYFYTLDWHEAQDGRFLLQLPNVQPPSSGIYSATYLEASPLGSAFFRLIVRGCGAGRWGPGCTKECPGCLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPGISGCRGLTFCLPDPYGCSCGSGWRGSQCQEACAPGHFGADCRLQCQCQNGGTCDRFSGCVCPSGWHGVHCEKSDRIPQILNMASELEFNLETMPRINCAAAGNPFPVRGSIELRKPDGTVLLSTKAIVEPEKTTAEFEVPRLVLADSGFWECRVSTSGGQDSRRFKVNVKVPPVPLAAPRLLTKQSRQLVVSPLVSFSGDGPISTVRLHYRPQDSTMDWSTIVVDPSENVTLMNLRPKTGYSVRVQLSRPGEGGEGAWGPPTLMTTDCPEPLLQPWLEGWHVEGTDRLRVSWSLPLVPGPLVGDGFLLRLWDGTRGQERRENVSSPQARTALLTGLTPGTHYQLDVQLYHCTLLGPASPPAHVLLPPSGPPAPRHLHAQALSDSEIQLTWKHPEALPGPISKYVVEVQVAGGAGDPLWIDVDRPEETSTIIRGLNASTRYLFRMRASIQGLGDWSNTVEESTLGNGLQAEGPVQESRAAEEGLDQQLILAVVGSVSATCLTILAALLTLVCIRRSCLHRRRTFTYQSGSGEETILQFSSGTLTLTRRPKLQPEPLSYPVLEWEDITFEDLIGEGNFGQVIRAMIKKDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLGACKNRGYLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDAANGMQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSRGEEVYVKKTMGRLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLEARKAYVNMSLFENFTYAGIDATAEEA Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 469308 | TIE1 | tyrosine kinase with immunoglobulin like and EGF like domains 1 | 9598 | VGNC:7007 | OMA, EggNOG |
| Macaque | 702208 | TIE1 | tyrosine kinase with immunoglobulin like and EGF like domains 1 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 21846 | Tie1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 10090 | MGI:99906 | Inparanoid, OMA, EggNOG |
| Rat | 89806 | Tie1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 10116 | RGD:621642 | Inparanoid, OMA, EggNOG |
| Dog | 482535 | TIE1 | tyrosine kinase with immunoglobulin like and EGF like domains 1 | 9615 | VGNC:47366 | Inparanoid, OMA, EggNOG |
| Horse | 100066563 | TIE1 | tyrosine kinase with immunoglobulin like and EGF like domains 1 | 9796 | VGNC:24101 | Inparanoid, OMA, EggNOG |
| Cow | 280941 | TIE1 | tyrosine kinase with immunoglobulin like and EGF like domains 1 | 9913 | VGNC:35861 | Inparanoid, OMA, EggNOG |
| Pig | 494022 | TIE1 | tyrosine kinase with immunoglobulin like and EGF like domains 1 | 9823 | OMA, EggNOG | |
| Opossum | 100025707 | TIE1 | tyrosine kinase with immunoglobulin like and EGF like domains 1 | 13616 | Inparanoid, OMA, EggNOG | |
| Chicken | 424562 | TIE1 | tyrosine kinase with immunoglobulin like and EGF like domains 1 | 9031 | CGNC:7566 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100565697 | tie1 | tyrosine kinase with immunoglobulin like and EGF like domains 1 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100496664 | tie1 | tyrosine kinase with immunoglobulin like and EGF like domains 1 | 8364 | XB-GENE-922217 | Inparanoid, OMA, EggNOG |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / TK group / TIE family / Tyrosine-protein kinase receptor tie-1
protein / Kinase / Protein kinase / TK group / TIE family / Tyrosine-protein kinase receptor tie-1
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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