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ATP2A1

DescriptionSarcoplasmic/endoplasmic reticulum calcium ATPase 1

Gene and Protein Information

Gene ID487
Uniprot Accession IDs O14983 A8K5J9 B3KY17 O14984 SERCA1
Ensembl ID ENSP00000349595
Symbol ATP2A SERCA1
FamilyBelongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
Sequence
MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGPVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWLMVLKISLPVIGLDEILKFVARNYLEDPEDERRK
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp454019ATP2A1ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 19598VGNC:9020OMA, EggNOG
Mouse11937Atp2a1ATPase, Ca++ transporting, cardiac muscle, fast twitch 110090MGI:105058Inparanoid, OMA, EggNOG
Dog479797ATP2A1ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 19615VGNC:38253Inparanoid, OMA
Horse100064403ATP2A1ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 19796VGNC:15650Inparanoid, OMA
Cow518117ATP2A1ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 19913VGNC:26290Inparanoid, OMA
Pig100516962ATP2A1ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 19823Inparanoid, OMA
Anole lizard100554310atp2a1ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 128377Inparanoid, OMA
Xenopus613090atp2a1ATPase, Ca++ transporting, cardiac muscle, fast twitch 18364XB-GENE-975115Inparanoid, OMA
Zebrafish494489atp2a1lATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like7955ZDB-GENE-041229-2Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    transporter    /    ion channel    /    Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
protein    /    transporter    /    cation transporter    /    Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
protein    /    transporter    /    hydrolase    /    Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
DTO Classes
protein    /    Transporter    /    P-type ATPases    /    Ca2+-ATPases    /    Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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