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| Description | H(+)/Cl(-) exchange transporter 3 |
|---|
Gene and Protein Information
| Gene ID | 1182 |
|---|---|
| Uniprot Accession IDs | P51790 B7Z932 B9EGJ9 D3DP34 E9PB97 O14918 Q86Z21 |
| Ensembl ID | ENSP00000261514 |
| Symbol | CLC3 ClC-3 |
| Family | Belongs to the chloride channel (TC 2.A.49) family. ClC-3/CLCN3 subfamily. |
| Sequence | MESEQLFHRGYYRNSYNSITSASSDEELLDGAGVIMDFQTSEDDNLLDGDTAVGTHYTMTNGGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKCKDRERHRRINSKKKESAWEMTKSLYDAWSGWLVVTLTGLASGALAGLIDIAADWMTDLKEGICLSALWYNHEQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVACCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIRANIAWCRRRKSTKFGKYPVLEVIIVAAITAVIAFPNPYTRLNTSELIKELFTDCGPLESSSLCDYRNDMNASKIVDDIPDRPAGIGVYSAIWQLCLALIFKIIMTVFTFGIKVPSGLFIPSMAIGAIAGRIVGIAVEQLAYYHHDWFIFKEWCEVGADCITPGLYAMVGAAACLGGVTRMTVSLVVIVFELTGGLEYIVPLMAAVMTSKWVGDAFGREGIYEAHIRLNGYPFLDAKEEFTHTTLAADVMRPRRNDPPLAVLTQDNMTVDDIENMINETSYNGFPVIMSKESQRLVGFALRRDLTIAIESARKKQEGIVGSSRVCFAQHTPSLPAESPRPLKLRSILDMSPFTVTDHTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDILRHMAQTANQDPASIMFN Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 471346 | CLCN3 | chloride voltage-gated channel 3 | 9598 | VGNC:7416 | OMA, EggNOG |
| Macaque | 694472 | CLCN3 | chloride voltage-gated channel 3 | 9544 | OMA, EggNOG | |
| Mouse | 12725 | Clcn3 | chloride channel, voltage-sensitive 3 | 10090 | MGI:103555 | Inparanoid, OMA, EggNOG |
| Rat | 84360 | Clcn3 | chloride voltage-gated channel 3 | 10116 | RGD:621219 | Inparanoid, OMA, EggNOG |
| Dog | 477354 | CLCN3 | chloride voltage-gated channel 3 | 9615 | VGNC:39303 | Inparanoid, OMA, EggNOG |
| Horse | 100061225 | CLCN3 | chloride voltage-gated channel 3 | 9796 | VGNC:16577 | Inparanoid, OMA, EggNOG |
| Cow | 522719 | CLCN3 | chloride voltage-gated channel 3 | 9913 | VGNC:27397 | Inparanoid, OMA, EggNOG |
| Pig | 100156049 | CLCN3 | chloride voltage-gated channel 3 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100021050 | CLCN3 | chloride voltage-gated channel 3 | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | 100074971 | CLCN3 | chloride voltage-gated channel 3 | 9258 | Inparanoid, OMA, EggNOG | |
| Chicken | 422432 | CLCN3 | chloride voltage-gated channel 3 | 9031 | CGNC:7357 | Inparanoid, OMA |
| Anole lizard | 100567534 | clcn3 | chloride voltage-gated channel 3 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100216107 | clcn3 | chloride channel, voltage-sensitive 3 | 8364 | XB-GENE-950794 | Inparanoid, OMA, EggNOG |
| Zebrafish | 559340 | clcn3 | chloride channel 3 | 7955 | ZDB-GENE-030131-1699 | Inparanoid, OMA |
| C. elegans | 174449 | clh-5 | Chloride channel protein | 6239 | OMA, EggNOG | |
| S.cerevisiae | 853497 | GEF1 | Gef1p | 4932 | S000003801 | Inparanoid, OMA, EggNOG |
Protein Classes
DTO Classes
protein / Ion channel / Chloride channel family / ClC-3/CLCN3 subfamily / H(+)/Cl(-) exchange transporter 3
protein / Ion channel / Chloride channel family / ClC-3/CLCN3 subfamily / H(+)/Cl(-) exchange transporter 3
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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