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PTK2

DescriptionFocal adhesion kinase 1

Gene and Protein Information

Gene ID5747
Uniprot Accession IDs Q05397 B4E2N6 F5H4S4 J3QT16 Q14291 Q8IYN9 Q9UD85 FADK 1
Ensembl ID ENSP00000341189
Symbol FAK FAK1 FAK FADK FAK1 FRNK PPP1R71 p125FAK pp125FAK
FamilyBelongs to the protein kinase superfamily. Tyr protein kinase family. FAK subfamily.
Sequence
MAAAYLDPNLNHTPNSSTKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGTSQSFIIRPQKEGERALPSIPKLANSEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSYNEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp464422PTK2protein tyrosine kinase 29598VGNC:813OMA, EggNOG
Mouse14083Ptk2PTK2 protein tyrosine kinase 210090MGI:95481Inparanoid, OMA, EggNOG
Rat25614Ptk2protein tyrosine kinase 210116RGD:3443Inparanoid, OMA, EggNOG
Dog475108PTK2protein tyrosine kinase 29615VGNC:45158Inparanoid, OMA, EggNOG
Horse100058245PTK2protein tyrosine kinase 29796VGNC:22002Inparanoid, OMA, EggNOG
Cow506270PTK2protein tyrosine kinase 29913VGNC:33518Inparanoid, OMA, EggNOG
Opossum100027188PTK2protein tyrosine kinase 213616Inparanoid, OMA, EggNOG
Platypus100076789PTK2protein tyrosine kinase 29258Inparanoid, OMA, EggNOG
Anole lizard100554871ptk2protein tyrosine kinase 228377Inparanoid, OMA
Xenopus733890ptk2protein tyrosine kinase 28364XB-GENE-952025Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TK group    /    FAK family    /    Focal adhesion kinase 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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