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PSEN2

DescriptionPresenilin-2

Gene and Protein Information

Gene ID5664
Uniprot Accession IDs P49810 A8K8D4 B1AP21 Q96P32 PS-2
Ensembl ID ENSP00000355747
Symbol AD4 PS2 PSNL2 STM2 AD4 PS2 AD3L STM2 CMD1V
FamilyBelongs to the peptidase A22A family.
Sequence
MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDPDRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLTGYPGEELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp457790PSEN2presenilin 29598VGNC:1474OMA, EggNOG
Macaque698770PSEN2presenilin 29544Inparanoid, OMA, EggNOG
Mouse19165Psen2presenilin 210090MGI:109284Inparanoid, OMA, EggNOG
Rat81751Psen2presenilin 210116RGD:621060Inparanoid, OMA, EggNOG
Dog490382PSEN2presenilin 29615VGNC:45086Inparanoid, OMA, EggNOG
Horse100054506PSEN2presenilin 29796VGNC:21930Inparanoid, OMA, EggNOG
Cow282010PSEN2presenilin 29913VGNC:33435Inparanoid, OMA, EggNOG
Pig780410PSEN2presenilin 29823Inparanoid, OMA, EggNOG
Opossum100026453PSEN2presenilin 213616Inparanoid, OMA, EggNOG
PlatypusPSEN2presenilin 2 [Source:HGNC Symbol;Acc:HGNC:9509]9258OMA, EggNOG
Chicken374188PSEN2presenilin 29031CGNC:6904Inparanoid, OMA
Anole lizard100567182psen2presenilin 228377Inparanoid, OMA
Xenopus549935psen2presenilin 28364XB-GENE-854877Inparanoid, OMA
Zebrafish58026psen2presenilin 27955ZDB-GENE-000330-9Inparanoid, OMA
C. elegans180441sel-12Presenilin sel-126239Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    signaling molecule    /    membrane-bound signaling molecule    /    Presenilin-2
protein    /    signaling molecule    /    aspartic protease    /    Presenilin-2
protein    /    signaling molecule    /    protease    /    Presenilin-2
protein    /    signaling molecule    /    calcium-binding protein    /    Presenilin-2
protein    /    signaling molecule    /    hydrolase    /    Presenilin-2
DTO Classes
protein    /    Enzyme    /    Protease    /    Aspartic protease    /    Presenilin-2

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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