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GRIN1

DescriptionGlutamate receptor ionotropic, NMDA 1

Gene and Protein Information

Gene ID2902
Uniprot Accession IDs Q05586 A6NLK7 A6NLR1 C9K0X1 P35437 Q12867 Q12868 Q5VSF3 Q5VSF4 Q5VSF5 Q5VSF6 Q5VSF7 Q5VSF8 Q9UPF8 Q9UPF9 GluN1
Ensembl ID ENSP00000360608
Symbol NMDAR1 NR1 MRD8 GluN1 NMDA1 NDHMSD NDHMSR NMD-R1 NMDAR1
FamilyBelongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
Sequence
MSTMRLLTLALLFSCSVARAACDPKIVNIGAVLSTRKHEQMFREAVNQANKRHGSWKIQLNATSVTHKPNAIQMALSVCEDLISSQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLGLTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYSWNHIILLVSDDHEGRAAQKRLETLLEERESKAEKVLQFDPGTKNVTALLMEAKELEARVIILSASEDDAATVYRAAAMLNMTGSGYVWLVGEREISGNALRYAPDGILGLQLINGKNESAHISDAVGVVAQAVHELLEKENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKPRGYQMSTRLKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDLDKTWVRYQECDSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRKQMQLAFAAVNVWRKNLQDRKSGRAEPDPKKKATFRAITSTLASSFKRRRSSKDTSTGGGRGALQNQKDTVLPRRAIEREEGQLQLCSRHRES
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp465176GRIN1glutamate ionotropic receptor NMDA type subunit 19598VGNC:53282Inparanoid, OMA, EggNOG
Macaque574380GRIN1glutamate ionotropic receptor NMDA type subunit 19544Inparanoid, OMA
Mouse14810Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)10090MGI:95819Inparanoid, OMA, EggNOG
Rat24408Grin1glutamate ionotropic receptor NMDA type subunit 110116RGD:2736Inparanoid, OMA, EggNOG
Dog494007GRIN1glutamate ionotropic receptor NMDA type subunit 19615VGNC:41491OMA, EggNOG
Horse100059861GRIN1glutamate ionotropic receptor NMDA type subunit 19796VGNC:18588Inparanoid, OMA, EggNOG
Cow100336579GRIN1glutamate ionotropic receptor NMDA type subunit 19913VGNC:29645Inparanoid, OMA, EggNOG
Opossum100023485GRIN1glutamate ionotropic receptor NMDA type subunit 113616Inparanoid, EggNOG
Platypus100082705GRIN1glutamate ionotropic receptor NMDA type subunit 19258Inparanoid, EggNOG
Chicken404296GRIN1glutamate ionotropic receptor NMDA type subunit 19031CGNC:6756Inparanoid, OMA
Anole lizard100553024grin1glutamate ionotropic receptor NMDA type subunit 128377Inparanoid, OMA, EggNOG
Xenopus780048grin1glutamate ionotropic receptor NMDA type subunit 18364XB-GENE-494200Inparanoid, OMA, EggNOG
Zebrafish100005675grin1bglutamate receptor, ionotropic, N-methyl D-aspartate 1b7955ZDB-GENE-051202-2OMA, EggNOG
Zebrafish767745grin1aglutamate receptor, ionotropic, N-methyl D-aspartate 1a7955ZDB-GENE-051202-1Inparanoid, OMA
C. elegans173929nmr-1NMDA class glutamate Receptor6239Inparanoid, OMA
Fruitfly40665Nmdar1NMDA receptor 17227FBgn0010399Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Ion channel    /    Glutamate-gated ion channel (GIC) Family of Neurotransmitter Receptors    /    NR1/GRIN1 subfamily    /    Glutamate receptor ionotropic, nmda 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

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