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| Description | DNA ligase 1 |
|---|
Gene and Protein Information
| Gene ID | 3978 |
|---|---|
| Uniprot Accession IDs | P18858 B2RAI8 B4DTU4 Q2TB12 Q32P23 |
| Ensembl ID | ENSP00000263274 |
| Family | Belongs to the ATP-dependent DNA ligase family. |
| Sequence | MQRSIMSFFHPKKEGKAKKPEKEASNSSRETEPPPKAALKEWNGVVSESDSPVKRPGRKAARVLGSEGEEEDEALSPAKGQKPALDCSQVSPPRPATSPENNASLSDTSPMDSSPSGIPKRRTARKQLPKRTIQEVLEEQSEDEDREAKRKKEEEEEETPKESLTEAEVATEKEGEDGDQPTTPPKPLKTSKAETPTESVSEPEVATKQELQEEEEQTKPPRRAPKTLSSFFTPRKPAVKKEVKEEEPGAPGKEGAAEGPLDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQEDNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQSQIQNQQGEDSGSDPEDTY Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 468936 | LIG1 | DNA ligase 1 | 9598 | VGNC:10202 | OMA, EggNOG |
| Macaque | 718528 | LIG1 | DNA ligase 1 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 16881 | Lig1 | ligase I, DNA, ATP-dependent | 10090 | MGI:101789 | Inparanoid, OMA, EggNOG |
| Rat | 100911727 | LOC100911727 | DNA ligase 1-like | 10116 | RGD:6491367 | Inparanoid, OMA, EggNOG |
| Dog | 100686967 | LIG1 | DNA ligase 1 | 9615 | VGNC:42673 | Inparanoid, OMA, EggNOG |
| Horse | 100053186 | LIG1 | DNA ligase 1 | 9796 | VGNC:19663 | Inparanoid, OMA, EggNOG |
| Cow | 100124507 | LIG1 | DNA ligase 1 | 9913 | VGNC:30882 | Inparanoid, OMA, EggNOG |
| Pig | 100520434 | LIG1 | DNA ligase 1 | 9823 | Inparanoid, OMA, EggNOG | |
| Platypus | 100086878 | LIG1 | DNA ligase 1 | 9258 | OMA, EggNOG | |
| Anole lizard | 100565521 | lig1 | DNA ligase 1 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100271763 | lig1 | ligase I, DNA, ATP-dependent | 8364 | XB-GENE-1009779 | Inparanoid, OMA, EggNOG |
| Zebrafish | 556995 | lig1 | ligase I, DNA, ATP-dependent | 7955 | ZDB-GENE-110404-2 | OMA, EggNOG |
| C. elegans | 179502 | lig-1 | DNA ligase 1 | 6239 | Inparanoid, OMA, EggNOG | |
| Fruitfly | 37791 | DNA-ligI | DNA ligase I | 7227 | FBgn0262619 | Inparanoid, OMA, EggNOG |
| S.cerevisiae | 851391 | CDC9 | DNA ligase (ATP) CDC9 | 4932 | S000002323 | Inparanoid, OMA, EggNOG |
Protein Classes
PANTHER Classes
protein / nucleic acid binding / DNA binding protein / DNA ligase 1
protein / nucleic acid binding / DNA ligase / DNA ligase 1
protein / nucleic acid binding / ligase / DNA ligase 1
protein / nucleic acid binding / DNA binding protein / DNA ligase 1
protein / nucleic acid binding / DNA ligase / DNA ligase 1
protein / nucleic acid binding / ligase / DNA ligase 1
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
|---|
Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
|---|
Bibliography
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