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PSEN1

DescriptionPresenilin-1

Gene and Protein Information

Gene ID5663
Uniprot Accession IDs P49768 B2R6D3 O95465 Q14762 Q15719 Q15720 Q96P33 Q9UIF0 PS-1
Ensembl ID ENSP00000326366
Symbol AD3 PS1 PSNL1 AD3 FAD PS1 PS-1 S182 ACNINV3
FamilyBelongs to the peptidase A22A family.
Sequence
MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIYLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEGDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAAVQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp739740PSEN1presenilin 19598VGNC:3326OMA, EggNOG
Macaque696274PSEN1presenilin 19544Inparanoid, OMA, EggNOG
Mouse19164Psen1presenilin 110090MGI:1202717Inparanoid, OMA, EggNOG
Rat29192Psen1presenilin 110116RGD:3425Inparanoid, OMA, EggNOG
Dog403408PSEN1presenilin 19615VGNC:45085Inparanoid, OMA, EggNOG
HorsePSEN1presenilin 1 [Source:HGNC Symbol;Acc:HGNC:9508]9796OMA, EggNOG
Cow282705PSEN1presenilin 19913VGNC:33434Inparanoid, OMA, EggNOG
Pig780411PSEN1presenilin 19823Inparanoid, OMA, EggNOG
Opossum100019628PSEN1presenilin 113616Inparanoid, EggNOG
Platypus100091250PSEN1presenilin 19258OMA, EggNOG
Chicken373977PSEN1presenilin 19031CGNC:7083Inparanoid, OMA
Anole lizard100553615psen1presenilin 128377Inparanoid, OMA
Xenopus394924psen1presenilin 18364XB-GENE-481916Inparanoid, OMA, EggNOG
Zebrafish30221psen1presenilin 17955ZDB-GENE-991119-4Inparanoid, OMA
C. elegans180441sel-12Presenilin sel-126239OMA, EggNOG
Fruitfly40260PsnPresenilin7227FBgn0019947Inparanoid, EggNOG

Protein Classes

PANTHER Classes
protein    /    signaling molecule    /    membrane-bound signaling molecule    /    Presenilin-1
protein    /    signaling molecule    /    aspartic protease    /    Presenilin-1
protein    /    signaling molecule    /    protease    /    Presenilin-1
protein    /    signaling molecule    /    calcium-binding protein    /    Presenilin-1
protein    /    signaling molecule    /    hydrolase    /    Presenilin-1
DTO Classes
protein    /    Enzyme    /    Protease    /    Aspartic protease    /    Presenilin-1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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