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NSD2

DescriptionHistone-lysine N-methyltransferase NSD2

Gene and Protein Information

Gene ID7468
Uniprot Accession IDs O96028 A2A2T2 A2A2T3 A2A2T4 A7MCZ1 D3DVQ2 O96031 Q4VBY8 Q672J1 Q6IS00 Q86V01 Q9BZB4 Q9UI92 Q9UPR2
Ensembl ID ENSP00000372351
Symbol KIAA1090 MMSET TRX5 WHSC1 WHS TRX5 KMT3F KMT3G MMSET WHSC1 REIIBP
FamilyBelongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
Sequence
MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLEQGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp461070NSD2nuclear receptor binding SET domain protein 29598VGNC:48886OMA, EggNOG
Mouse107823Nsd2nuclear receptor binding SET domain protein 210090MGI:1276574Inparanoid, OMA, EggNOG
Rat680537Nsd2nuclear receptor binding SET domain protein 210116RGD:1307955OMA, EggNOG
Dog479077NSD2nuclear receptor binding SET domain protein 29615VGNC:43981OMA, EggNOG
Horse100051090NSD2nuclear receptor binding SET domain protein 29796VGNC:20898OMA, EggNOG
Cow540769NSD2nuclear receptor binding SET domain protein 29913VGNC:32272OMA, EggNOG
Pig100515039NSD2nuclear receptor binding SET domain protein 29823OMA, EggNOG
Opossum100022914NSD2nuclear receptor binding SET domain protein 213616OMA, EggNOG
Chicken422897WHSC1Wolf-Hirschhorn syndrome candidate 19031CGNC:11713Inparanoid, OMA, EggNOG
Anole lizard100563747nsd2nuclear receptor binding SET domain protein 228377OMA, EggNOG
Xenopus100125213nsd2nuclear receptor binding SET domain protein 28364XB-GENE-988824OMA, EggNOG
Fruitfly43351NSDNuclear receptor binding SET domain protein7227FBgn0039559OMA, EggNOG

Protein Classes

DTO Classes
protein    /    Epigenetic regulator    /    Writer    /    Protein methyltransferase    /    SET domain    /    Histone-lysine N-methyltransferase NSD2

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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