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JAK2

DescriptionTyrosine-protein kinase JAK2

Gene and Protein Information

Gene ID3717
Uniprot Accession IDs O60674 O14636 O75297
Ensembl ID ENSP00000371067
Symbol JTK10 THCYT3
FamilyBelongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
Sequence
MGMACLTMTEMEGTSTSSIYQNGDISGNANSMKQIDPVLQVYLYHSLGKSEADYLTFPSGEYVAEEICIAASKACGITPVYHNMFALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYFPRWYCSGSNRAYRHGISRGAEAPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQEECLGMAVLDMMRIAKENDQTPLAIYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQFSQCKATARNLKLKYLINLETLQSAFYTEKFEVKEPGSGPSGEEIFATIIITGNGGIQWSRGKHKESETLTEQDLQLYCDFPNIIDVSIKQANQEGSNESRVVTIHKQDGKNLEIELSSLREALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp464979JAK2Janus kinase 29598VGNC:4770OMA, EggNOG
Macaque694184JAK2Janus kinase 29544Inparanoid, OMA, EggNOG
Mouse16452Jak2Janus kinase 210090MGI:96629Inparanoid, OMA, EggNOG
Rat24514Jak2Janus kinase 210116RGD:2939Inparanoid, OMA
Dog484185JAK2Janus kinase 29615VGNC:42176Inparanoid, OMA
Horse100051487JAK2Janus kinase 29796VGNC:19213Inparanoid, OMA
Cow525246JAK2Janus kinase 29913VGNC:30365Inparanoid, OMA
Pig397201JAK2Janus kinase 29823Inparanoid, OMA
Opossum100017930JAK2Janus kinase 213616Inparanoid, OMA
Platypus100074305JAK2Janus kinase 29258Inparanoid, OMA
Chicken374199JAK2Janus kinase 29031CGNC:11173Inparanoid, OMA
Anole lizard100552375jak2Janus kinase 228377Inparanoid, OMA
Xenopus100036599jak2Janus kinase 2 (a protein tyrosine kinase)8364XB-GENE-483712Inparanoid, OMA
Zebrafish30298jak2bJanus kinase 2b7955ZDB-GENE-980526-123Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TK group    /    JAKA family    /    Tyrosine-protein kinase jak2

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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