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METTL3

DescriptionN6-adenosine-methyltransferase catalytic subunit

Gene and Protein Information

Gene ID56339
Uniprot Accession IDs Q86U44 O14736 Q86V05 Q9HB32
Ensembl ID ENSP00000298717
Symbol MTA70 M6A IME4 Spo8 MT-A70 hMETTL3
FamilyBelongs to the MT-A70-like family.
Sequence
MSDTWSSIQAHKKQLDSLRERLQRRRKQDSGHLDLRNPEAALSPTFRSDSPVPTAPTSGGPKPSTASAVPELATDPELEKKLLHHLSDLALTLPTDAVSICLAISTPDAPATQDGVESLLQKFAAQELIEVKRGLLQDDAHPTLVTYADHSKLSAMMGAVAEKKGPGEVAGTVTGQKRRAEQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLNQQSTKEQQSKKVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFRRIINKHTDESLGDCSFLNTCFHMDTCKYVHYEIDACMDSEAPGSKDHTPSQELALTQSVGGDSSADRLFPPQWICCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRRLNIPVLQDDGFLFLWVTGRAMELGRECLNLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGVKGNPQGFNQGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQLDGIHLLDPDVVARFKQRYPDGIISKPKNL
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp452765METTL3methyltransferase like 39598VGNC:3382Inparanoid, OMA, EggNOG
MacaqueSALL2spalt like transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:10526]9544OMA, EggNOG
Mouse56335Mettl3methyltransferase like 310090MGI:1927165Inparanoid, OMA, EggNOG
Rat361035Mettl3methyltransferase-like 310116RGD:1311750Inparanoid, OMA, EggNOG
Dog475404METTL3methyltransferase like 39615VGNC:43177Inparanoid, OMA, EggNOG
Horse100059413METTL3methyltransferase like 39796VGNC:20130Inparanoid, OMA, EggNOG
Cow540339METTL3methyltransferase like 39913VGNC:31412Inparanoid, OMA, EggNOG
Pig100513294METTL3methyltransferase like 39823Inparanoid, OMA, EggNOG
Opossum100023433METTL3methyltransferase like 313616Inparanoid, EggNOG
Anole lizard100557846mettl3methyltransferase like 328377Inparanoid, OMA, EggNOG
Xenopus549173mettl3methyltransferase like 38364XB-GENE-922807Inparanoid, OMA, EggNOG
Zebrafish100004398mettl3methyltransferase like 37955ZDB-GENE-030131-9498Inparanoid, OMA, EggNOG
Fruitfly42844Ime4Inducer of meiosis 47227FBgn0039139Inparanoid, EggNOG

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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