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| Description | Dual specificity mitogen-activated protein kinase kinase 1 |
|---|
Gene and Protein Information
| Gene ID | 5604 |
|---|---|
| Uniprot Accession IDs | Q02750 MAP kinase kinase 1 |
| Ensembl ID | ENSP00000302486 |
| Symbol | MEK1 PRKMK1 CFC3 MEK1 MKK1 MAPKK1 PRKMK1 |
| Family | Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily. |
| Sequence | MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 450188 | MAP2K1 | mitogen-activated protein kinase kinase 1 | 9598 | VGNC:7531 | Inparanoid, OMA, EggNOG |
| Macaque | 710415 | MAP2K1 | mitogen-activated protein kinase kinase 1 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 26395 | Map2k1 | mitogen-activated protein kinase kinase 1 | 10090 | MGI:1346866 | Inparanoid, OMA, EggNOG |
| Rat | 170851 | Map2k1 | mitogen activated protein kinase kinase 1 | 10116 | RGD:70495 | Inparanoid, OMA, EggNOG |
| Dog | 478347 | MAP2K1 | mitogen-activated protein kinase kinase 1 | 9615 | VGNC:42960 | Inparanoid, OMA, EggNOG |
| Horse | 100065996 | MAP2K1 | mitogen-activated protein kinase kinase 1 | 9796 | VGNC:19926 | Inparanoid, OMA, EggNOG |
| Cow | 533199 | MAP2K1 | mitogen-activated protein kinase kinase 1 | 9913 | VGNC:31183 | Inparanoid, OMA |
| Opossum | 100018410 | MAP2K1 | mitogen-activated protein kinase kinase 1 | 13616 | Inparanoid, EggNOG | |
| Platypus | MAP2K1 | mitogen-activated protein kinase kinase 1 [Source:HGNC Symbol;Acc:HGNC:6840] | 9258 | OMA, EggNOG | ||
| Chicken | 415549 | MAP2K1 | mitogen-activated protein kinase kinase 1 | 9031 | CGNC:50013 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100567176 | map2k2 | mitogen-activated protein kinase kinase 2 | 28377 | Inparanoid, EggNOG | |
| Xenopus | 493420 | map2k1 | mitogen-activated protein kinase kinase 1 | 8364 | XB-GENE-478822 | Inparanoid, OMA, EggNOG |
| Zebrafish | 406728 | map2k1 | mitogen-activated protein kinase kinase 1 | 7955 | ZDB-GENE-040426-2759 | Inparanoid, OMA, EggNOG |
| C. elegans | 171872 | mek-2 | Dual specificity mitogen-activated protein kinase kinase mek-2 | 6239 | Inparanoid, OMA |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / STE group / STE7 family / Dual specificity mitogen-activated protein kinase kinase 1
protein / Kinase / Protein kinase / STE group / STE7 family / Dual specificity mitogen-activated protein kinase kinase 1
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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