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| Description | Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial |
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Gene and Protein Information
| Gene ID | 10797 |
|---|---|
| Uniprot Accession IDs | P13995 Q53G90 Q53GV5 Q53S36 Q7Z650 |
| Ensembl ID | ENSP00000377617 |
| Symbol | NMDMC NMDMC |
| Family | Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family. |
| Sequence | MAATSLMSALAARLLQPAHSCSLRLRPFHLAAVRNEAVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVILVGENPASHSYVLNKTRAAAVVGINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGINRVHDPVTAKPKLVGDVDFEGVRQKAGYITPVPGGVGPMTVAMLMKNTIIAAKKVLRLEEREVLKSKELGVATN Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 459331 | MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 9598 | OMA, EggNOG | |
| Mouse | 17768 | Mthfd2 | methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase | 10090 | MGI:1338850 | Inparanoid, OMA, EggNOG |
| Rat | 680308 | Mthfd2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 10116 | RGD:1311313 | Inparanoid, OMA, EggNOG |
| Dog | 483107 | MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 9615 | Inparanoid, OMA, EggNOG | |
| Horse | 100053990 | MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 9796 | Inparanoid, OMA | |
| Cow | 517539 | MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 9913 | Inparanoid, OMA, EggNOG | |
| Opossum | MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [Source:HGNC Symbol;Acc:HGNC:7434] | 13616 | Inparanoid, EggNOG | ||
| Anole lizard | 100566586 | mthfd2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 28377 | Inparanoid, OMA | |
| Xenopus | 100170462 | mthfd2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 8364 | XB-GENE-941965 | Inparanoid, OMA |
| Zebrafish | 100004977 | mthfd2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 7955 | ZDB-GENE-040704-20 | Inparanoid, OMA |
| S.cerevisiae | 853955 | MTD1 | methylenetetrahydrofolate dehydrogenase (NAD(+)) | 4932 | S000001788 | Inparanoid, OMA |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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