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| Description | NPC intracellular cholesterol transporter 1 |
|---|
Gene and Protein Information
| Gene ID | 4864 |
|---|---|
| Uniprot Accession IDs | O15118 B4DET3 Q9P130 |
| Ensembl ID | ENSP00000269228 |
| Symbol | NPC POGZ SLC65A1 |
| Family | Belongs to the patched family. |
| Sequence | MTARGLALGLLLLLLCPAQVFSQSCVWYGECGIAYGDKRYNCEYSGPPKPLPKDGYDLVQELCPGFFFGNVSLCCDVRQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATEDYVDPVTNQTKTNVKELQYYVGQSFANAMYNACRDVEAPSSNDKALGLLCGKDADACNATNWIEYMFNKDNGQAPFTITPVFSDFPVHGMEPMNNATKGCDESVDEVTAPCSCQDCSIVCGPKPQPPPPPAPWTILGLDAMYVIMWITYMAFLLVFFGAFFAVWCYRKRYFVSEYTPIDSNIAFSVNASDKGEASCCDPVSAAFEGCLRRLFTRWGSFCVRNPGCVIFFSLVFITACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKHIYQPYPSGADVPFGPPLDIQILHQVLDLQIAIENITASYDNETVTLQDICLAPLSPYNTNCTILSVLNYFQNSHSVLDHKKGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTEKLQRAQAWEKEFINFVKNYKNPNLTISFTAERSIEDELNRESDSDVFTVVISYAIMFLYISLALGHMKSCRRLLVDSKVSLGIAGILIVLSSVACSLGVFSYIGLPLTLIVIEVIPFLVLAVGVDNIFILVQAYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLGALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCVRGAEDGTSVQASESCLFRFFKNSYSPLLLKDWMRPIVIAIFVGVLSFSIAVLNKVDIGLDQSLSMPDDSYMVDYFKSISQYLHAGPPVYFVLEEGHDYTSSKGQNMVCGGMGCNNDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRVDNITDQFCNASVVDPACVRCRPLTPEGKQRPQGGDFMRFLPMFLSDNPNPKCGKGGHAAYSSAVNILLGHGTRVGATYFMTYHTVLQTSADFIDALKKARLIASNVTETMGINGSAYRVFPYSVFYVFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCELWSAVIMCATIAMVLVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRVERAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVNKAKSCATEERYKGTERERLLNF Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 455338 | NPC1 | NPC intracellular cholesterol transporter 1 | 9598 | VGNC:10461 | OMA, EggNOG |
| Macaque | 700835 | NPC1 | NPC intracellular cholesterol transporter 1 | 9544 | OMA, EggNOG | |
| Mouse | 18145 | Npc1 | NPC intracellular cholesterol transporter 1 | 10090 | MGI:1097712 | Inparanoid, OMA, EggNOG |
| Rat | 266732 | Npc1 | NPC intracellular cholesterol transporter 1 | 10116 | RGD:628693 | Inparanoid, OMA, EggNOG |
| Dog | 403698 | NPC1 | NPC intracellular cholesterol transporter 1 | 9615 | VGNC:43913 | Inparanoid, OMA, EggNOG |
| Horse | 100059175 | NPC1 | NPC intracellular cholesterol transporter 1 | 9796 | VGNC:20831 | Inparanoid, OMA, EggNOG |
| Cow | 286772 | NPC1 | NPC intracellular cholesterol transporter 1 | 9913 | VGNC:32194 | Inparanoid, OMA, EggNOG |
| Pig | 397591 | NPC1 | NPC intracellular cholesterol transporter 1 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100011777 | NPC1 | NPC intracellular cholesterol transporter 1 | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | 100092266 | NPC1 | NPC intracellular cholesterol transporter 1 | 9258 | Inparanoid, OMA, EggNOG | |
| Chicken | 421076 | NPC1 | NPC intracellular cholesterol transporter 1 | 9031 | CGNC:11176 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100561824 | npc1 | NPC intracellular cholesterol transporter 1 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | npc1 | NPC intracellular cholesterol transporter 1 [Source:Xenbase;Acc:XB-GENE-984654] | 8364 | OMA, EggNOG | ||
| Zebrafish | 553330 | npc1 | Niemann-Pick disease, type C1 | 7955 | ZDB-GENE-030131-3161 | Inparanoid, OMA, EggNOG |
| C. elegans | 176165 | ncr-2 | Niemann-Pick C1 protein homolog 2 | 6239 | OMA, EggNOG | |
| Fruitfly | 34358 | Npc1a | Niemann-Pick type C-1a | 7227 | FBgn0024320 | Inparanoid, EggNOG |
| S.cerevisiae | 856101 | NCR1 | sphingolipid transporter | 4932 | S000005927 | OMA, EggNOG |
Protein Classes
DTO Classes
protein / Transporter / SLC superfamily of solute carriers / SLC65 NPC-type cholesterol transporters / Niemann-Pick C1 protein
protein / Transporter / SLC superfamily of solute carriers / SLC65 NPC-type cholesterol transporters / Niemann-Pick C1 protein
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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