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DHODH

DescriptionDihydroorotate dehydrogenase (quinone), mitochondrial

Gene and Protein Information

Gene ID1723
Uniprot Accession IDs Q02127 A8K8C8 Q6P176 DHOdehase
Ensembl ID ENSP00000219240
Symbol URA1 POADS DHOdehase
FamilyBelongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
Sequence
MAWRHLKKRAQDAVIILGGGGLLFASYLMATGDERFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLPRARFQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHRR
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp454232DHODHdihydroorotate dehydrogenase (quinone)9598VGNC:13696OMA, EggNOG
Macaque706936DHODHdihydroorotate dehydrogenase (quinone)9544Inparanoid, OMA, EggNOG
Mouse56749Dhodhdihydroorotate dehydrogenase10090MGI:1928378Inparanoid, OMA
Rat65156Dhodhdihydroorotate dehydrogenase (quinone)10116RGD:68352Inparanoid, OMA, EggNOG
Dog610755DHODHdihydroorotate dehydrogenase (quinone)9615VGNC:53333Inparanoid, OMA, EggNOG
Horse100067925DHODHdihydroorotate dehydrogenase (quinone)9796VGNC:53551Inparanoid, OMA, EggNOG
Opossum100028673DHODHdihydroorotate dehydrogenase (quinone)13616Inparanoid, EggNOG
PlatypusDHODHdihydroorotate dehydrogenase (quinone) [Source:HGNC Symbol;Acc:HGNC:2867]9258OMA, EggNOG
Chicken415876DHODHdihydroorotate dehydrogenase (quinone)9031CGNC:514Inparanoid, OMA, EggNOG
Anole lizard100562179dhodhdihydroorotate dehydrogenase (quinone)28377Inparanoid, EggNOG
Xenopus594963dhodhdihydroorotate dehydrogenase (quinone)8364XB-GENE-967864Inparanoid, OMA, EggNOG
Zebrafish494065dhodhdihydroorotate dehydrogenase7955ZDB-GENE-030131-3157Inparanoid, OMA, EggNOG
C. elegans172392dhod-1Dihydroorotate dehydrogenase (quinone), mitochondrial6239Inparanoid, OMA
Fruitfly41022DhodDihydroorotate dehydrogenase7227FBgn0000447Inparanoid, OMA, EggNOG
S.cerevisiae853664URA1dihydroorotate dehydrogenase4932S000001699Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    oxidoreductase    /    dehydrogenase    /    Dihydroorotate dehydrogenase (quinone), mitochondrial
protein    /    oxidoreductase    /    reductase    /    Dihydroorotate dehydrogenase (quinone), mitochondrial
DTO Classes
protein    /    Enzyme    /    Oxidoreductase    /    Dehydrogenase    /    Dihydroorotate dehydrogenase (quinone), mitochondrial

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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